日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

ENPP1抑制剂具有超长的药物靶点停留时间,可作为一种先天免疫检查点阻断疗法用于癌症治疗。

Songnan Wang ,Randolph M Johnson ,Jacqueline A Carozza ,Daniel Fernandez ,Jan Scicinski ,Neil A Verity ,Rachel Mardjuki ,Xujun Cao ,Yingjie Guo ,Jacqueline Papkoff ,Nigel Ray ,Lingyin Li

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy

ENPP1抑制剂具有超长的药物靶点停留时间,可作为一种先天免疫检查点阻断疗法用于癌症治疗。

Johnson, Randolph M; Wang, Songnan; Carozza, Jacqueline A; Fernandez, Daniel; Scicinski, Jan; Verity, Neil A; Mardjuki, Rachel; Cao, Xujun; Papkoff, Jacqueline; Ray, Nigel; Li, Lingyin

Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis

干扰素诱导的跨膜蛋白1在血管生成过程中调节内皮细胞腔的形成

Popson, Stephanie A; Ziegler, Mary E; Chen, Xiaofang; Holderfield, Matthew T; Shaaban, Cameron I; Fong, Ashley H; Welch-Reardon, Katrina M; Papkoff, Jackie; Hughes, Christopher C W

Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras

Nox1在人类结肠癌中过度表达,并与K-Ras的激活突变相关。

Laurent, Eunice; McCoy, James W 3rd; Macina, Roberto A; Liu, Wenhui; Cheng, Guangjie; Robine, Sylvie; Papkoff, Jackie; Lambeth, J David

Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

Wnt-1调节游离的catenin蛋白池并稳定APC-catenin复合物。

Papkoff, J; Rubinfeld, B; Schryver, B; Polakis, P

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

Wnt-1通过稳定β-catenin与细胞黏附蛋白钙黏蛋白的结合来调节哺乳动物细胞间的黏附。

Hinck, L; Nelson, W J; Papkoff, J

p42 mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation

在凝血酶诱导的血小板活化和聚集过程中,p42丝裂原活化蛋白激酶和p90核糖体S6激酶被选择性磷酸化和激活。

Papkoff, J; Chen, R H; Blenis, J; Forsman, J

Wnt family proteins are secreted and associated with the cell surface

Wnt家族蛋白是分泌蛋白,并与细胞表面相关。

Smolich, B D; McMahon, J A; McMahon, A P; Papkoff, J

Secreted int-1 protein is associated with the cell surface

分泌型int-1蛋白与细胞表面相关

Papkoff, J; Schryver, B

Inducible overexpression and secretion of int-1 protein

int-1蛋白的诱导性过表达和分泌

Papkoff, J