ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy
ENPP1抑制剂具有超长的药物靶点停留时间,可作为一种先天免疫检查点阻断疗法用于癌症治疗。
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doi:10.1101/2025.05.18.654655
Johnson, Randolph M; Wang, Songnan; Carozza, Jacqueline A; Fernandez, Daniel; Scicinski, Jan; Verity, Neil A; Mardjuki, Rachel; Cao, Xujun; Papkoff, Jacqueline; Ray, Nigel; Li, Lingyin