Parakala相关文献与解析，生知库 | 链接生命科学的每一步

Algorithmic Identification of Treatment-Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease

利用大型语言模型从临床记录中算法识别治疗期间出现的不良事件：一项炎症性肠病试点研究

Silverman, Anna L; Sushil, Madhumita; Bhasuran, Balu; Ludwig, Dana; Buchanan, James; Racz, Rebecca; Parakala, Mahalakshmi; El-Kamary, Samer; Ahima, Ohenewaa; Belov, Artur; Choi, Lauren; Billings, Monisha; Li, Yan; Habal, Nadia; Liu, Qi; Tiwari, Jawahar; Butte, Atul J; Rudrapatna, Vivek A

炎症/感染

炎症

发表日期：2024

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The rat bladder umbrella cell keratin network: Organization, dependence on the plectin cytolinker, and responses to bladder filling

大鼠膀胱伞状细胞角蛋白网络：组织结构、对plectin细胞连接蛋白的依赖性以及对膀胱充盈的反应

期刊:Molecular Biology of the Cell

影响因子:3.1

doi:10.1091/mbc.E24-06-0262

Wily G Ruiz，Dennis R Clayton，Tanmay Parakala-Jain，Marianela G Dalghi，Jonathan Franks，Gerard Apodaca

The umbrella cell keratin network: organization as a tile-like mesh, formation of a girded layer in response to bladder filling, and dependence on the plectin cytolinker

伞细胞角蛋白网络：组织成瓦片状网格，响应膀胱充盈形成带状层，并依赖于网蛋白细胞连接体

期刊:

影响因子:

doi:10.1101/2024.06.11.598498

Wily G Ruiz, Dennis R Clayton, Tanmay Parakala-Jain, Marianela G Dalghi, Jonathan Franks, Gerard Apodaca

Antinociceptive effect of the calcitonin gene-related peptide receptor antagonist BIBN4096BS in mice with bacterial cystitis

降钙素基因相关肽受体拮抗剂BIBN4096BS对细菌性膀胱炎小鼠的抗伤害作用

期刊:American Journal of Physiology-Renal Physiology

影响因子:3.7

doi:10.1152/ajprenal.00217.2023

Nicolas Montalbetti, Marianela G Dalghi, Tanmay Parakala-Jain, Dennis Clayton, Gerard Apodaca, Marcelo D Carattino

微生物学

发表日期：2023

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Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

神经甾体对 GABA 能抑制的代谢性（而非变构性）作用取决于 GABAA 受体的磷酸化

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA119.008875

Manasa L Parakala, Yihui Zhang, Amit Modgil, Jayashree Chadchankar, Thuy N Vien, Michael A Ackley, James J Doherty, Paul A Davies, Stephen J Moss

GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization

VTA 多巴胺神经元中的 GIRK 电流控制小鼠对可卡因诱导的运动敏化的敏感性

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1807788115

Robert A Rifkin, Deborah Huyghe, Xiaofan Li, Manasa Parakala, Erin Aisenberg, Stephen J Moss, Paul A Slesinger

Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism

内源性和合成的神经活性类固醇通过蛋白激酶C依赖性机制，持续增强GABA能抑制的效力。

期刊:Neuropharmacology

影响因子:4.6

doi:10.1016/j.neuropharm.2016.10.010

Modgil, Amit; Parakala, Manasa L; Ackley, Michael A; Doherty, James J; Moss, Stephen J; Davies, Paul A

信号转导

发表日期：2017

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Conditional deletion of Tmem63b does not impact mouse voiding behavior

条件性敲除Tmem63b基因并不影响小鼠的排尿行为。

Algorithmic Identification of Treatment-Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease

利用大型语言模型从临床记录中算法识别治疗期间出现的不良事件：一项炎症性肠病试点研究

The rat bladder umbrella cell keratin network: Organization, dependence on the plectin cytolinker, and responses to bladder filling

大鼠膀胱伞状细胞角蛋白网络：组织结构、对plectin细胞连接蛋白的依赖性以及对膀胱充盈的反应

The umbrella cell keratin network: organization as a tile-like mesh, formation of a girded layer in response to bladder filling, and dependence on the plectin cytolinker

伞细胞角蛋白网络：组织成瓦片状网格，响应膀胱充盈形成带状层，并依赖于网蛋白细胞连接体

Antinociceptive effect of the calcitonin gene-related peptide receptor antagonist BIBN4096BS in mice with bacterial cystitis

降钙素基因相关肽受体拮抗剂BIBN4096BS对细菌性膀胱炎小鼠的抗伤害作用

Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

神经甾体对 GABA 能抑制的代谢性（而非变构性）作用取决于 GABAA 受体的磷酸化

GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization

VTA 多巴胺神经元中的 GIRK 电流控制小鼠对可卡因诱导的运动敏化的敏感性

Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism

内源性和合成的神经活性类固醇通过蛋白激酶C依赖性机制，持续增强GABA能抑制的效力。