日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Diffusion kurtosis imaging detects cortical microstructural alterations in amyloid-positive MCI patients

扩散峰度成像可检测淀粉样蛋白阳性轻度认知障碍患者的皮质微结构改变

Nielsen, Rune B; Parbo, Peter; Ismail, Rola; B Dalby, Rikke; Tietze, Anna; Brændgaard, Hans; Gottrup, Hanne; Brooks, David J; Østergaard, Leif; Eskildsen, Simon F

Microglial activation is raised in preclinical Alzheimer's disease and associated with covert memory impairment

在阿尔茨海默病临床前期,小胶质细胞活化增强,且与隐性记忆障碍相关。

Kjeldsen, Pernille Louise; Madsen, Lasse Stensvig; Parbo, Peter; Ismail, Rola; Aanerud, Joel Fredrik Astrup; Kaasing, Malene; Damholdt, Malene Flensborg; Eskildsen, Simon Fristed; Østergaard, Leif; Brooks, David James

Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment

淀粉样β蛋白聚集体激活轻度认知障碍中的外周单核细胞

Kristian Juul-Madsen ,Peter Parbo ,Rola Ismail ,Peter L Ovesen ,Vanessa Schmidt ,Lasse S Madsen ,Jacob Thyrsted ,Sarah Gierl ,Mihaela Breum ,Agnete Larsen ,Morten N Andersen ,Marina Romero-Ramos ,Christian K Holm ,Gregers R Andersen ,Huaying Zhao ,Peter Schuck ,Jens V Nygaard ,Duncan S Sutherland ,Simon F Eskildsen ,Thomas E Willnow ,David J Brooks ,Thomas Vorup-Jensen

Microglial responses partially mediate the effect of Aβ on cognition in Alzheimer's disease

小胶质细胞反应部分介导了Aβ对阿尔茨海默病认知功能的影响

Madsen, Lasse S; Ismail, Rola; Parbo, Peter; Kjeldsen, Pernille L; Schaldemose, Jeppe L; Hansen, Kim V; Gottrup, Hanne; Aanerud, Joel; Eskildsen, Simon F; Brooks, David J

Capillary dysfunction in healthy elderly APOE ε4 carriers with raised brain Aβ deposition

健康老年APOE ε4携带者脑内Aβ沉积增加,伴有毛细血管功能障碍。

Madsen, Lasse S; Kjeldsen, Pernille L; Ismail, Rola; Parbo, Peter; Østergaard, Leif; Brooks, David J; Eskildsen, Simon F

Asymmetric amyloid deposition in preclinical Alzheimer's disease: A PET study

临床前阿尔茨海默病中淀粉样蛋白沉积的不对称性:一项PET研究

Kjeldsen, Pernille L; Parbo, Peter; Hansen, Kim V; Aanerud, Joel F A; Ismail, Rola; Nissen, Peter H; Dalby, Rikke B; Damholdt, Malene F; Borghammer, Per; Brooks, David J

Capillary function progressively deteriorates in prodromal Alzheimer's disease: A longitudinal MRI perfusion study

阿尔茨海默病前驱期毛细血管功能逐渐恶化:一项纵向磁共振灌注研究

Madsen, Lasse S; Nielsen, Rune B; Parbo, Peter; Ismail, Rola; Mikkelsen, Irene K; Gottrup, Hanne; Østergaard, Leif; Brooks, David J; Eskildsen, Simon F

The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study

阿尔茨海默病中神经炎症、β-淀粉样蛋白和tau蛋白沉积之间的关系:一项纵向PET研究

Ismail, Rola; Parbo, Peter; Madsen, Lasse Stensvig; Hansen, Allan K; Hansen, Kim V; Schaldemose, Jeppe L; Kjeldsen, Pernille L; Stokholm, Morten G; Gottrup, Hanne; Eskildsen, Simon F; Brooks, David J

Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease

血浆神经丝轻链水平降低与皮质小胶质细胞活化增强相关,提示炎症可能对阿尔茨海默病前驱期起到保护作用。

Parbo, Peter; Madsen, Lasse Stensvig; Ismail, Rola; Zetterberg, Henrik; Blennow, Kaj; Eskildsen, Simon F; Vorup-Jensen, Thomas; Brooks, David J

Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers

对无症状LRRK2突变携带者进行多巴胺功能和微胶质细胞成像

Gersel Stokholm, Morten; Garrido, Alicia; Tolosa, Eduardo; Serradell, Mónica; Iranzo, Alex; Østergaard, Karen; Borghammer, Per; Møller, Arne; Parbo, Peter; Stær, Kristian; Brooks, David J; Martí, Maria José; Pavese, Nicola