日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities

多平台分子分析揭示了两种具有不同治疗弱点的恶性周围神经鞘瘤亚组

Suganth Suppiah, Sheila Mansouri #, Yasin Mamatjan #, Jeffrey C Liu #, Minu M Bhunia, Vikas Patil, Prisni Rath, Bharati Mehani, Pardeep Heir, Severa Bunda, German L Velez-Reyes, Olivia Singh, Nazanin Ijad, Neda Pirouzmand, Tatyana Dalcourt, Ying Meng, Shirin Karimi, Qingxia Wei, Farshad Nassiri, Tre

c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein

c-Src 磷酸化并抑制 CIC 肿瘤抑制蛋白的功能

Severa Bunda, Pardeep Heir, Annie Si Cong Li, Yasin Mamatjan, Gelareh Zadeh, Kenneth Aldape

CIC protein instability contributes to tumorigenesis in glioblastoma

CIC 蛋白不稳定性导致胶质母细胞瘤的发生

Severa Bunda, Pardeep Heir, Julie Metcalf, Annie Si Cong Li, Sameer Agnihotri, Stefan Pusch, Mamatjan Yasin, Mira Li, Kelly Burrell, Sheila Mansouri, Olivia Singh, Mark Wilson, Amir Alamsahebpour, Romina Nejad, Bethany Choi, David Kim, Andreas von Deimling, Gelareh Zadeh, Kenneth Aldape

Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling

促红细胞生成素受体周转和信号传导的氧依赖性调节

Pardeep Heir, Tharan Srikumar, George Bikopoulos, Severa Bunda, Betty P Poon, Jeffrey E Lee, Brian Raught, Michael Ohh

Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL)

底物与 Von Hippel-Lindau 肿瘤抑制蛋白 (VHL) 的羟基化依赖性相互作用

Pardeep Heir, Michael Ohh

Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis

抑制SHP2介导的Ras去磷酸化可抑制肿瘤发生

Severa Bunda, Kelly Burrell, Pardeep Heir, Lifan Zeng, Amir Alamsahebpour, Yoshihito Kano, Brian Raught, Zhong-Yin Zhang, Gelareh Zadeh, Michael Ohh

DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase

DCNL1 作为底物传感器和 cullin 2-RING 连接酶的激活剂发挥作用

Pardeep Heir, Roxana I Sufan, Samantha N Greer, Betty P Poon, Jeffrey E Lee, Michael Ohh