The tobacco-specific carcinogen NNK induces pulmonary tumorigenesis via nAChR/Src/STAT3-mediated activation of the renin-angiotensin system and IGF-1R signaling
烟草特异性致癌物NNK通过nAChR/Src/STAT3介导的肾素-血管紧张素系统和IGF-1R信号通路激活诱导肺部肿瘤发生。
期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-023-00994-2
Boo, Hye-Jin; Min, Hye-Young; Hwang, Su Jung; Lee, Hyo-Jong; Lee, Jae-Won; Oh, Sei-Ryang; Park, Choon-Sik; Park, Jong-Sook; Lee, You Mie; Lee, Ho-Young
肿瘤
肿瘤免疫
JAK/STAT
信号转导
AChR
STAT3
IGF-1
