日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates.

在非人灵长类动物中快速诱导产生针对 HIV-1 Env V3 糖表位的 Asn332 糖基化非依赖性中和抗体。

Relano-Rodriguez Ignacio, Du Jianqiu, Lin Zi Jie, Kerwin Margaret, Tarquis-Medina Marta, Urbano Eduardo, Cui Jiayan, Watkins Meagan, Lavine Christy L, Zhao Peng, Habib Rumi, Agostino Colby, Ghosh Sukanya, Park Joyce, Boroughs Caroline, Walsh Agnes A, Melo Mariane B, Shukla Niharika, Shaw George M, Hahn Beatrice H, Irvine Darrell J, Wells Lance, Weiner David B, Seaman Michael S, Kulp Daniel W, Veazey Ronald S, Pallesen Jesper, Escolano Amelia

Immune-focused RBD nanoparticles induce cross-reactive, RBS-directed responses capable of variant-resistant SARS-CoV-2 neutralization

免疫靶向RBD纳米颗粒可诱导交叉反应性、RBS导向的免疫应答,从而实现对SARS-CoV-2变异株的中和作用

Konrath, Kylie M; Liaw, Kevin; Tursi, Nicholas J; McCanna, Madison E; Warner, Bryce M; Gary, Ebony N; Zhu, Xizhou; Livingston, Cory; Monastra, Cara; Frase, Drew; Chokkalingam, Neethu; Huynh, Alana; Shupin, Nicholas; Bayruns, Kelly; Kriete, Sinja; Kim, Amber; Park, Joyce; Vendramelli, Robert; Truong, Thang; Tierney, Kevin; Azaransky, Kimberly; Moffat, Estella; Embury-Hyatt, Carissa; Beer, Lynn A; Solanke, Oreoluwa; Walker, Susanne N; Kalia, Richa; Tang, Hsin-Yao; Humeau, Laurent M P F; Smith, Trevor R F; Kobasa, Darwyn; Weiner, David B; Kulp, Daniel W

Machine learning enables de novo multiepitope design of Plasmodium falciparum circumsporozoite protein to target trimeric L9 antibody

机器学习能够对恶性疟原虫环子孢子蛋白进行从头多表位设计,以靶向三聚体L9抗体

Nelson, J Andrew D; Garfinkle, Samuel E; Lin, Zi Jie; Park, Joyce; Kim, Amber J; Bayruns, Kelly; McCanna, Madison E; Konrath, Kylie M; Agostino, Colby J; Kulp, Daniel W; Odom John, Audrey R; Pallesen, Jesper

Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV.

HPV稳定化、扩增表位纳米颗粒疫苗的结构工程

Helble Michaela, Zhu Xizhou, Bhojnagarwala Pratik S, Liaw Kevin, Gao Yangcheng, Kim Amber, Bayruns Kelly, McCanna Madison E, Park Joyce, Konrath Kylie M, Garfinkle Sam, Brysgel Taylor, Weiner David B, Kulp Daniel W

Machine learning enables de novo multi-epitope design of plasmodium falciparum circumsporozoite protein to target trimeric L9 antibody

机器学习技术能够从头设计恶性疟原虫环子孢子蛋白的多表位,以靶向三聚体L9抗体

Nelson, J Andrew D; Garfinkle, Samuel E; Lin, Zi Jie; Park, Joyce; Kim, Amber J; Bayruns, Kelly; McCanna, Madison E; Konrath, Kylie M; Agostino, Colby J; Kulp, Daniel W; John, Audrey R Odom; Pallesen, Jesper

Deep Mining of the Human Antibody Repertoire Identifies Frequent and Genetically Diverse CDRH3 Topologies Targetable by Vaccination

对人类抗体库的深度挖掘发现了可通过疫苗接种靶向的常见且遗传多样性丰富的CDRH3拓扑结构

Habib, Rumi; Solieva, Shahlo O; Lin, Zi Jie; Ghosh, Sukanya; Bayruns, Kelly; Singh, Maya; Agostino, Colby J; Tursi, Nicholas J; Sowers, Kirsten J; Huang, Jinwei; Roark, Ryan S; Purwar, Mansi; Park, Younghoon; Ayyanathan, Kasirajan; Li, Hui; Carey, John W; Kim, Amber; Park, Joyce; McCanna, Madison E; Skelly, Ashwin N; Chokkalingam, Neethu; Kriete, Sinja; Shupin, Nicholas; Huynh, Alana; Walker, Susanne; Sadeesh, Roopak; Laenger, Niklas; Du, Jianqiu; Cui, Jiayan; Patel, Ami; Escolano, Amelia; Kwong, Peter D; Shapiro, Lawrence; Bowman, Gregory R; Hahn, Beatrice H; Shaw, George M; Weiner, David B; Pallesen, Jesper; Kulp, Daniel W

The Comparative Sufficiency of ChatGPT, Google Bard, and Bing AI in Answering Diagnosis, Treatment, and Prognosis Questions About Common Dermatological Diagnoses

ChatGPT、Google Bard 和 Bing AI 在回答常见皮肤病诊断、治疗和预后问题方面的比较效能

Chau, Courtney A; Feng, Hao; Cobos, Gabriela; Park, Joyce

Authors' Reply: The Importance of Comparing New Technologies (AI) to Existing Tools for Patient Education on Common Dermatologic Conditions: A Commentary

作者回复:比较新技术(人工智能)与现有工具在常见皮肤病患者教育中的重要性:评述

Chau, Courtney; Feng, Hao; Cobos, Gabriela; Park, Joyce

Rapid elicitation of a new class of neutralizing N332-glycan independent V3-glycan antibodies against HIV-1 in nonhuman primates

在非人灵长类动物中快速诱导产生一类新型的针对 HIV-1 的中和性 N332 糖基化非依赖性 V3 糖基化抗体

Relano-Rodriguez, Ignacio; Du, Jianqiu; Lin, Zi Jie; Kerwin, Margaret; Tarquis-Medina, Marta; Urbano, Eduardo; Cui, Jiayan; Watkins, Meagan; Zhao, Peng; Habib, Rumi; Ghosh, Sukanya; Park, Joyce; Boroughs, Caroline; Walsh, Agnes A; Melo, Mariane B; Shaw, George M; Hahn, Beatrice H; Irvine, Darrell J; Wells, Lance; Weiner, David B; Kulp, Daniel W; Veazey, Ronald S; Pallesen, Jesper; Escolano, Amelia

Chromatinization modulates topoisomerase II processivity

染色质化调节拓扑异构酶II的加工性

Jaeyoon Lee, Meiling Wu, James T Inman, Gundeep Singh, Seong Ha Park, Joyce H Lee, Robert M Fulbright, Yifeng Hong, Joshua Jeong, James M Berger, Michelle D Wang