日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety and Immunogenicity of an rVSV Lassa Fever Vaccine Candidate

rVSV拉沙热候选疫苗的安全性和免疫原性

Malkin, Elissa; Zaric, Marija; Kieh, Mark; Baden, Lindsey R; Fitz-Patrick, David; Marini, Arianna; Yun, Heejin; Hayes, Peter; Bromell, Rachel; Ayorinde, Morolayo; Fernandez, Natalia; Varma, Ruhani; Sigei, Faith; Ward, Matthew; Pindolia, Hema; Sewell, Shayna; Amini, Fahimah; Blie, Julie; Wilson, Barthalomew; Faley, Patrick; McCullough, John; Tokpah, Franklin; Wisseh, Cecelia; Towalid, Elvis; Hadawale, Swapnil; Sayeed, Eddy; Hunt, Devin; Keshavarzi, Nahid; Barin, Burc; Maljkovic Berry, Irina; Parks, Christopher L; Truter, Shobhna Gopal; Walker, Kathleen; Vekemans, Johan; Lehrman, Jennifer; Engelbrecht, Michelle; Malherbe, Mariette; Laufer, Dagna; Philiponis, Vincent; Higgs, Elizabeth; Mutua, Gaudensia; Fast, Patricia E; Gupta, Swati B

Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials

一种基于具有复制能力的疱疹性口炎病毒的拉沙病毒候选疫苗的临床前开发已进入人体临床试验阶段。

Cooper, Christopher L; Morrow, Gavin; Yuan, Maoli; Postler, Thomas S; Neal, Maxwell L; Cross, Robert W; Woolsey, Courtney; Agans, Krystle N; Borisevich, Viktoriya; McNamara, Ryan P; Atyeo, Caroline; Roy, Vicky; Germosen, Daritza; Hou, Fuxiang; Li, Shui L; Reiserova, Lucia; Choi, Yesle; Wilson, Aaron; Wagner, Denise; Wallace-Selman, Olivia; Carpov, Alexei; Geng, Fuqiang; Frederick, Deborah J; DeStefano, Joanne; Ercolini, Anne M; Enriquez, Adrian S; Hastie, Kathryn M; Ramos da Silva, Suzane; Sayeed, Eddy; Coleman, John W; Kilianski, Andrew; Alter, Galit; Saphire, Erica Ollmann; Aitchison, John D; Geisbert, Thomas W; Gupta, Swati B; Feinberg, Mark B; Parks, Christopher L

Mapping the antibody response to Lassa virus vaccination of non-human primates

绘制非人灵长类动物对拉沙病毒疫苗接种的抗体反应图谱

Enriquez, Adrian S; Avalos, Ruben Diaz; Parekh, Diptiben; Cooper, Christopher L; Morrow, Gavin; Geisbert, Thomas W; Parks, Christopher L; Hastie, Kathryn M; Saphire, Erica Ollmann

An Intranasal Challenge Model in African Green Monkeys (Chlorocebus aethiops) for Mild-to-Moderate COVID-19 Disease Caused by Subvariant XBB.1.5

非洲绿猴(Chlorocebus aethiops)鼻内感染模型研究由XBB.1.5亚型病毒引起的轻度至中度COVID-19疾病

Storm, Nadia; Lo, Ming; Crossland, Nicholas; Seyler-Schmidt, Margaux; Staples, Hilary; Silva-Ayala, Daniela; Laprise, Ambre M; St Denis, Lauren; Grosz, Kyle; O'Connell, Aoife; Gertje, Hans; Ripin, Tillie; Decker, Claire; Mazur, M; Thurman, Colleen; Espinoza, Marlene; Morrow, Gavin; Parks, Christopher L; Cooper, Christopher L; Griffiths, Anthony

An introduction to the Marburg virus vaccine consortium, MARVAC

马尔堡病毒疫苗联盟(MARVAC)简介

Cross, Robert W; Longini, Ira M; Becker, Stephan; Bok, Karin; Boucher, David; Carroll, Miles W; Díaz, Janet V; Dowling, William E; Draghia-Akli, Ruxandra; Duworko, James T; Dye, John M; Egan, Michael A; Fast, Patricia; Finan, Amy; Finch, Courtney; Fleming, Thomas R; Fusco, Joan; Geisbert, Thomas W; Griffiths, Anthony; Günther, Stephan; Hensley, Lisa E; Honko, Anna; Hunegnaw, Ruth; Jakubik, Jocelyn; Ledgerwood, Julie; Luhn, Kerstin; Matassov, Demetrius; Meshulam, Jeffrey; Nelson, Emily V; Parks, Christopher L; Rustomjee, Roxana; Safronetz, David; Schwartz, Lauren M; Smith, Dean; Smock, Paul; Sow, Ydrissa; Spiropoulou, Christina F; Sullivan, Nancy J; Warfield, Kelly L; Wolfe, Daniel; Woolsey, Courtney; Zahn, Roland; Henao-Restrepo, Ana María; Muñoz-Fontela, César; Marzi, Andrea

Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome

尽管接种疫苗后产生了针对整个SIV蛋白质组的免疫反应,但仍可通过直肠感染猴免疫缺陷病毒(SIV)SIVmac239。

Martins, Mauricio A; Gonzalez-Nieto, Lucas; Ricciardi, Michael J; Bailey, Varian K; Dang, Christine M; Bischof, Georg F; Pedreño-Lopez, Nuria; Pauthner, Matthias G; Burton, Dennis R; Parks, Christopher L; Earl, Patricia; Moss, Bernard; Rakasz, Eva G; Lifson, Jeffrey D; Desrosiers, Ronald C; Watkins, David I

First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus-Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens

首次人体评估鼻内给药的复制型仙台病毒载体HIV 1型Gag疫苗的安全性和免疫原性:在初免-加强免疫方案中诱导强效T细胞或抗体反应

Nyombayire, Julien; Anzala, Omu; Gazzard, Brian; Karita, Etienne; Bergin, Philip; Hayes, Peter; Kopycinski, Jakub; Omosa-Manyonyi, Gloria; Jackson, Akil; Bizimana, Jean; Farah, Bashir; Sayeed, Eddy; Parks, Christopher L; Inoue, Makoto; Hironaka, Takashi; Hara, Hiroto; Shu, Tsugumine; Matano, Tetsuro; Dally, Len; Barin, Burc; Park, Harriet; Gilmour, Jill; Lombardo, Angela; Excler, Jean-Louis; Fast, Patricia; Laufer, Dagna S; Cox, Josephine H

Development of a duplex real-time RT-qPCR assay to monitor genome replication, gene expression and gene insert stability during in vivo replication of a prototype live attenuated canine distemper virus vector encoding SIV gag

开发一种双重实时RT-qPCR检测方法,用于监测编码SIV gag的原型活减毒犬瘟热病毒载体在体内复制过程中的基因组复制、基因表达和基因插入稳定性。

Coleman, John W; Wright, Kevin J; Wallace, Olivia L; Sharma, Palka; Arendt, Heather; Martinez, Jennifer; DeStefano, Joanne; Zamb, Timothy P; Zhang, Xinsheng; Parks, Christopher L

Canine distemper virus neutralization activity is low in human serum and it is sensitive to an amino acid substitution in the hemagglutinin protein

犬瘟热病毒在人血清中的中和活性较低,且对血凝素蛋白中的氨基酸替换非常敏感。

Zhang, Xinsheng; Wallace, Olivia L; Domi, Arban; Wright, Kevin J; Driscoll, Jonathan; Anzala, Omu; Sanders, Eduard J; Kamali, Anatoli; Karita, Etienne; Allen, Susan; Fast, Pat; Gilmour, Jill; Price, Matt A; Parks, Christopher L

Vaccination with Gag, Vif, and Nef gene fragments affords partial control of viral replication after mucosal challenge with SIVmac239

接种 Gag、Vif 和 Nef 基因片段疫苗可部分控制 SIVmac239 黏膜攻击后的病毒复制。

Martins, Mauricio A; Wilson, Nancy A; Piaskowski, Shari M; Weisgrau, Kim L; Furlott, Jessica R; Bonaldo, Myrna C; Veloso de Santana, Marlon G; Rudersdorf, Richard A; Rakasz, Eva G; Keating, Karen D; Chiuchiolo, Maria J; Piatak, Michael Jr; Allison, David B; Parks, Christopher L; Galler, Ricardo; Lifson, Jeffrey D; Watkins, David I