Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes

与 X 连锁中性粒细胞减少症相关的激活 WASP 突变会导致肌动蛋白聚合增强、细胞骨架反应改变以及淋巴细胞基因组不稳定性