Parrino Barbara相关文献与解析，生知库 | 链接生命科学的每一步

Pecoraro, Camilla; Carbone, Daniela; Al Ostoot, Fares Hezam Mohammed; Vahabi, Mahrou; Lencioni, Giulia; Diana, Patrizia; Giovannetti, Elisa; Parrino, Barbara

肿瘤

肿瘤免疫

发表日期：2025

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Novel Pyrazolo [1,5-a]-1,3,5-Triazine Derivatives as CDK7 Inhibitors: Synthesis and Biological Insights in Pancreatic Ductal Adenocarcinoma Models

新型吡唑并[1,5-a]-1,3,5-三嗪衍生物作为CDK7抑制剂：合成及在胰腺导管腺癌模型中的生物学意义

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202500448

Carbone, Daniela; Terrana, Francesca; Sciuto, Ludovica; Pecoraro, Camilla; Xu, Geng; Cascioferro, Stella; Cirrincione, Girolamo; Peters, Godefridus J; Giovannetti, Elisa; Parrino, Barbara; Diana, Patrizia

Novel [1,3,4]Thiadiazole[3,2-a]pyrimidin-5-ones as Promising Biofilm Dispersal Agents against Relevant Gram-Positive and Gram-Negative Pathogens

新型[1,3,4]噻二唑[3,2-a]嘧啶-5-酮类化合物作为有前景的生物膜分散剂，可对抗相关的革兰氏阳性菌和革兰氏阴性菌

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md22030133

Carbone, Daniela; Pecoraro, Camilla; Scianò, Fabio; Catania, Valentina; Schillaci, Domenico; Manachini, Barbara; Cascioferro, Stella; Diana, Patrizia; Parrino, Barbara

微生物学

发表日期：2024

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Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma

海洋天然产物的结构改造启发了新型3-氨基-1,2,4-三嗪PDK抑制剂库的构建，该抑制剂具有抗胰腺导管腺癌的肿瘤活性。

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md21050288

Carbone, Daniela; De Franco, Michele; Pecoraro, Camilla; Bassani, Davide; Pavan, Matteo; Cascioferro, Stella; Parrino, Barbara; Cirrincione, Girolamo; Dall'Acqua, Stefano; Sut, Stefania; Moro, Stefano; Gandin, Valentina; Diana, Patrizia

1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1

1,3,4-噁二唑和1,3,4-噻二唑诺托普辛衍生物抗胰腺导管腺癌：合成、细胞毒活性及CDK1抑制作用

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md21070412

Carbone, Daniela; Pecoraro, Camilla; Panzeca, Giovanna; Xu, Geng; Roeten, Margot S F; Cascioferro, Stella; Giovannetti, Elisa; Diana, Patrizia; Parrino, Barbara

A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells

一种新型的基于恶二唑的拓扑生汀衍生物可调节细胞周期蛋白依赖性激酶1的表达，并对胰腺癌细胞发挥细胞毒性作用

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules27010019

Pecoraro, Camilla; Parrino, Barbara; Cascioferro, Stella; Puerta, Adrian; Avan, Amir; Peters, Godefridus J; Diana, Patrizia; Giovannetti, Elisa; Carbone, Daniela

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance.

噻唑、其苯并稠合体系和噻唑烷酮衍生物：对抗抗生素耐药性的多功能且有前途的工具

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.9b01245

Cascioferro Stella, Parrino Barbara, Carbone Daniela, Schillaci Domenico, Giovannetti Elisa, Cirrincione Girolamo, Diana Patrizia

Bat

发表日期：2020

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Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

海洋生物碱诺托普辛的噻唑类似物作为细菌生物膜形成的抑制剂

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules26010081

Carbone, Anna; Cascioferro, Stella; Parrino, Barbara; Carbone, Daniela; Pecoraro, Camilla; Schillaci, Domenico; Cusimano, Maria Grazia; Cirrincione, Girolamo; Diana, Patrizia

微生物学

发表日期：2020

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"Open Sesame?": Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer

“芝麻开门？”：人平衡型核苷转运蛋白-1的生物标志物状态及其在胰腺癌中吉西他滨摄取和细胞毒性中表达和活性的影响机制

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers12113206

Randazzo, Ornella; Papini, Filippo; Mantini, Giulia; Gregori, Alessandro; Parrino, Barbara; Liu, Daniel S K; Cascioferro, Stella; Carbone, Daniela; Peters, Godefridus J; Frampton, Adam E; Garajova, Ingrid; Giovannetti, Elisa

Human

发表日期：2020

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New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

具有细胞毒活性的新型1,2,4-恶二唑诺托普辛衍生物

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md17010035

Cascioferro, Stella; Attanzio, Alessandro; Di Sarno, Veronica; Musella, Simona; Tesoriere, Luisa; Cirrincione, Girolamo; Diana, Patrizia; Parrino, Barbara

细胞生物学

发表日期：2019

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New Marine-Inspired Oxadiazole Derivatives for Use Against Pancreatic Ductal Adenocarcinoma

用于治疗胰腺导管腺癌的新型海洋启发式噁二唑衍生物

Novel Pyrazolo [1,5-a]-1,3,5-Triazine Derivatives as CDK7 Inhibitors: Synthesis and Biological Insights in Pancreatic Ductal Adenocarcinoma Models

新型吡唑并[1,5-a]-1,3,5-三嗪衍生物作为CDK7抑制剂：合成及在胰腺导管腺癌模型中的生物学意义

Novel [1,3,4]Thiadiazole[3,2-a]pyrimidin-5-ones as Promising Biofilm Dispersal Agents against Relevant Gram-Positive and Gram-Negative Pathogens

新型[1,3,4]噻二唑[3,2-a]嘧啶-5-酮类化合物作为有前景的生物膜分散剂，可对抗相关的革兰氏阳性菌和革兰氏阴性菌

Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma

海洋天然产物的结构改造启发了新型3-氨基-1,2,4-三嗪PDK抑制剂库的构建，该抑制剂具有抗胰腺导管腺癌的肿瘤活性。

1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1

1,3,4-噁二唑和1,3,4-噻二唑诺托普辛衍生物抗胰腺导管腺癌：合成、细胞毒活性及CDK1抑制作用

A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells

一种新型的基于恶二唑的拓扑生汀衍生物可调节细胞周期蛋白依赖性激酶1的表达，并对胰腺癌细胞发挥细胞毒性作用

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance.

噻唑、其苯并稠合体系和噻唑烷酮衍生物：对抗抗生素耐药性的多功能且有前途的工具

Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

海洋生物碱诺托普辛的噻唑类似物作为细菌生物膜形成的抑制剂

"Open Sesame?": Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer

“芝麻开门？”：人平衡型核苷转运蛋白-1的生物标志物状态及其在胰腺癌中吉西他滨摄取和细胞毒性中表达和活性的影响机制

New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

具有细胞毒活性的新型1,2,4-恶二唑诺托普辛衍生物