Nordihydroguaiaretic acid attenuates TNFα-dependent intercellular adhesion molecule-1 expression in cultured human umbilical vein endothelial cells via targeting TNFα-PI3K-NF-κB-ICAM1 pathway
二氢愈创木酸通过靶向TNFα-PI3K-NF-κB-ICAM1通路,减弱培养的人脐静脉内皮细胞中TNFα依赖的细胞间黏附分子-1(ICAM-1)的表达。
期刊:BMC Microbiology
影响因子:4.2
doi:10.1186/s12866-026-04947-3
Moreno-León, Alejandro; López-Morales, Ane; Höfle, Ursula; Barral, Marta; Majó, Natàlia; Lavín, José Luis; Mukherjee, Tapan Kumar; Malik, Parth; Singh, Raj; Haribhai Patel, Vishal; Kumar, Raman
信号转导
ICAM1
细胞生物学
TNFα
NF-κB
内皮细胞