日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and dynamic pharmacology of μ-opioid receptor positive allosteric modulators

μ-阿片受体正向变构调节剂的发现和动态药理学

O'Brien, Evan S; Wang, Junzheng; Tanguturi, Parthasaradhireddy; Li, Mengchu; White, Elizabeth; Shiimura, Yuki; Paul, Barnali; Appourchaux, Kevin; Kumar, Kaavya Krishna; Huang, Weijiao; Majumdar, Susruta; Traynor, John R; Streicher, John M; Chen, Chunlai; Kobilka, Brian K

Brain Hsp90 Inhibition Mitigates Facial Allodynia in a Rat Model of CSD Headache and Upregulates Endocannabinoid Signaling in the PAG.

脑内 Hsp90 抑制可减轻大鼠皮层扩散性抑制性头痛模型中的面部异常性疼痛,并上调 PAG 中的内源性大麻素信号传导。

Palomino Seph M, Levine Aidan A, Liktor-Busa Erika, Tanguturi Parthasaradhireddy, Streicher John M, Largent-Milnes Tally M

Development of Delta Opioid Receptor Antagonists Which Prevent Alzheimer's Disease-Like Pathology in the 5X-Familial Alzheimer's Disease [5XFAD] Mouse Model

开发δ阿片受体拮抗剂以预防5X家族性阿尔茨海默病[5XFAD]小鼠模型中阿尔茨海默病样病理的发生

Tanguturi, Parthasaradhireddy; Mitchell, Stefanie; Moukha-Chafiq, Omar; Zhang, Sixue; Tillotson, John; Ananthan, Subramaniam; Augelli-Szafran, Corinne E; Streicher, John M

Inhibiting spinal cord-specific hsp90 isoforms reveals a novel strategy to improve the therapeutic index of opioid treatment

抑制脊髓特异性 HSP90 亚型揭示了一种提高阿片类药物治疗疗效指数的新策略

Duron, David I; Tanguturi, Parthasaradhireddy; Campbell, Christopher S; Chou, Kerry; Bejarano, Paul; Gabriel, Katherin A; Bowden, Jessica L; Mishra, Sanket; Brackett, Christopher; Barlow, Deborah; Houseknecht, Karen L; Blagg, Brian S J; Streicher, John M

The role of opioid receptors in modulating Alzheimer's Disease

阿片受体在调节阿尔茨海默病中的作用

Tanguturi, Parthasaradhireddy; Streicher, John M

Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity

基于结构的糖基化催产素类似物设计及其选择性和镇痛活性的提高

Szabó, Lajos Z; Tanguturi, Parthasaradhireddy; Goodman, Hannah J; Sprőber, Sára; Liu, Chenxi; Al-Obeidi, Fahad; Bartlett, Mitchell J; Falk, Torsten; Kumirov, Vlad K; Heien, M Leandro; Streicher, John M; Polt, Robin

Design of Analgesic Trivalent Peptides with Low Withdrawal Symptoms: Probing the Antinociceptive Profile of Novel Linear and Cyclic Peptides as Opioid Pan Ligands

设计具有低戒断症状的镇痛三价肽:探索新型线性和环状肽作为阿片类泛配体的镇痛特性

Stefanucci, Azzurra; Minosi, Paola; Pieretti, Stefano; Tanguturi, Parthasaradhireddy; Molnar, Gabriella; Scioli, Giuseppe; Marinaccio, Lorenza; Della Valle, Alice; Streicher, John M; Mollica, Adriano

Correction: Tanguturi et al. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. Molecules 2021, 26, 6693

更正:Tanguturi 等人,《新型δ阿片受体(DOR)反向激动剂和不可逆(非竞争性)拮抗剂的发现》,Molecules 2021, 26, 6693

Tanguturi, Parthasaradhireddy; Pathak, Vibha; Zhang, Sixue; Moukha-Chafiq, Omar; Augelli-Szafran, Corinne E; Streicher, John M

Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved In Vivo Antinociceptive Effect after Peripheral Administration

发现具有增强的κ阿片受体(KOR)选择性d-四肽,其外周给药后体内镇痛作用增强

Stefanucci, Azzurra; Della Valle, Alice; Scioli, Giuseppe; Marinaccio, Lorenza; Pieretti, Stefano; Minosi, Paola; Szucs, Edina; Benyhe, Sandor; Masci, Domiziana; Tanguturi, Parthasaradhireddy; Chou, Kerry; Barlow, Deborah; Houseknecht, Karen; Streicher, John M; Mollica, Adriano

Genome-Wide CRISPR/Cas9-Based Screening for Deubiquitinase Subfamily Identifies Ubiquitin-Specific Protease 11 as a Novel Regulator of Osteogenic Differentiation

基于全基因组 CRISPR/Cas9 的去泛素化酶亚家族筛选确定泛素特异性蛋白酶 11 是成骨分化的新型调节剂

Kamini Kaushal, Apoorvi Tyagi, Janardhan Keshav Karapurkar, Eun-Jung Kim, Parthasaradhireddy Tanguturi, Kye-Seong Kim, Han-Sung Jung, Suresh Ramakrishna