日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of a series of pyrrolo-pyrimidine-based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication

鉴定出一系列基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂,这些抑制剂能够抑制冠状病毒的复制

Pfannenstiel, Jessica J; Duong, Men Thi Hoai; Cluff, Daniel; Sherrill, Lavinia M; Colquhoun, Iain; Cadoux, Gabrielle; Thorne, Devyn; Pääkkönen, Johan; Schemmel, Nathaniel F; O'Connor, Joseph; Saenjamsai, Pradtahna; Feng, Mei; Parthasarathy, Srivatsan; Hageman, Michael J; Johnson, David K; Roy, Anuradha; Lehtiö, Lari; Ferraris, Dana V; Fehr, Anthony R

PARP14 is an interferon-induced host factor that promotes IFN production and affects the replication of multiple viruses

PARP14是一种干扰素诱导的宿主因子,它能促进干扰素的产生并影响多种病毒的复制。

Parthasarathy, Srivatsan; Saenjamsai, Pradtahna; Hao, Hongping; Ferkul, Anna; Pfannenstiel, Jessica J; Bejan, Daniel S; Chen, Yating; Suder, Ellen L; Schwarting, Nancy; Aikawa, Masanori; Muhlberger, Elke; Hume, Adam J; Orozco, Robin C; Sullivan, Christopher S; Cohen, Michael S; Davido, David J; Fehr, Anthony R

Immunogenicity of a trivalent haemorrhagic fever vaccine candidate against Sudan virus, Marburg virus and Lassa virus in an mpox vaccine.

三价出血热候选疫苗对苏丹病毒、马尔堡病毒和拉沙病毒的免疫原性(痘苗疫苗)

Pfranger Martina, Krause Nina, Asbach Benedikt, Meier Johannes, Carnell George, Scheer Lara, Kalender Anja, Brenner David, Tonks Paul, Frost Simon, Wright Edward, Jordan Ingo, Kennedy Emma, Hewson Roger, Blacklaws Barbara, Chan Andrew, Parthasarathy Srivatsan, Dowall Stuart, Carroll Miles, Sandig Volker, Fedosyuk Sofiya, Kinsley Rebecca, Heeney Jonathan, Wagner Ralf

IFN-γ signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice

IFN-γ信号传导是鼠肝炎病毒(MHV)JHM株在感染小鼠脑内有效复制所必需的。

Kerr, Catherine M; Proctor-Roser, Macie A; Parthasarathy, Srivatsan; O'Connor, Joseph J; Pfannenstiel, Jessica J; Orozco, Robin C; Fehr, Anthony R

Mutation of a highly conserved isoleucine residue in loop 2 of several β-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental for replication

多个β冠状病毒宏结构域2环中高度保守的异亮氨酸残基的突变表明,增强的ADP-核糖结合不利于病毒复制。

Kerr, Catherine M; Pfannenstiel, Jessica J; Alhammad, Yousef M; O'Connor, Joseph J; Ghimire, Roshan; Shrestha, Rakshya; Khattabi, Reem; Saenjamsai, Pradtahna; Parthasarathy, Srivatsan; McDonald, Peter R; Gao, Philip; Johnson, David K; More, Sunil; Roy, Anuradha; Channappanavar, Rudragouda; Fehr, Anthony R

PARP14: A key ADP-ribosylating protein in host-virus interactions?

PARP14:宿主-病毒相互作用中的关键ADP核糖基化蛋白?

Parthasarathy, Srivatsan; Fehr, Anthony R

Influence of the Alternative Sigma Factor RpoN on Global Gene Expression and Carbon Catabolism in Enterococcus faecalis V583

替代σ因子RpoN对粪肠球菌V583中整体基因表达和碳代谢的影响

Keffeler, Erica C; Iyer, Vijayalakshmi S; Parthasarathy, Srivatsan; Ramsey, Matthew M; Gorman, Matthew J; Barke, Theresa L; Varahan, Sriram; Olson, Sally; Gilmore, Michael S; Abdullahi, Zakria H; Hancock, Emmaleigh N; Hancock, Lynn E

Involvement of Chromosomally Encoded Homologs of the RRNPP Protein Family in Enterococcus faecalis Biofilm Formation and Urinary Tract Infection Pathogenesis

染色体编码的RRNPP蛋白家族同源物参与粪肠球菌生物膜形成和尿路感染发病机制

Parthasarathy, Srivatsan; Jordan, Lorne D; Schwarting, Nancy; Woods, Megan A; Abdullahi, Zakria; Varahan, Sriram; Passos, Patricia M S; Miller, Brandy; Hancock, Lynn E