Discovery of BAY 3389934 Hydrochloride: A Potent and Selective Small-Molecule Dual Factor IIa/Xa Inhibitor with Short Half-Life for the Acute Treatment of Sepsis-Induced Coagulopathy
BAY 3389934 盐酸盐的发现：一种高效、选择性强的小分子双重因子 IIa/Xa 抑制剂，半衰期短，可用于急性治疗脓毒症引起的凝血功能障碍。
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00538
Beck, Hartmut; Mesch, Stefanie; Zimmermann, Stefanie; Vakalopoulos, Alexandros; Lehmann, Lutz; Gericke, Kersten Matthias; Süßmeier, Frank; Baerfacker, Lars; Hillisch, Alexander; Meier, Katharina; Tersteegen, Adrian; Buchmüller, Anja; Gerdes, Christoph; Dietze-Torres, Julia; Kersten, Elisabeth; Partikel, Katrin; Bröhl, Andreas; Levilain, Guillaume; Heitmeier, Stefan; Pfaff, Nils; Follmann, Markus
