日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein

鉴定对HSV1 ICP47蛋白抑制具有抗性的TAP2蛋白变体

Nagy, Gregory; Presley, Rebecca; Dhar, Shruti; Jeon, Hyeongseon; Moreira, Lynn; Tull, Olivia; Gupta, Arkobrato; Chung, Dongjun; Tsichlis, Philip N; Parvin, Jeffrey D

DNA repair function scores for 2172 variants in the BRCA1 amino-terminus

BRCA1氨基末端2172个变异体的DNA修复功能评分

Diabate, Mariame; Islam, Muhtadi M; Nagy, Gregory; Banerjee, Tapahsama; Dhar, Shruti; Smith, Nahum; Adamovich, Aleksandra I; Starita, Lea M; Parvin, Jeffrey D

Multiplexed assay of variant effect reveals residues of functional importance in the BRCA1 coiled-coil and serine cluster domains

多重变异效应分析揭示了BRCA1卷曲螺旋和丝氨酸簇结构域中具有功能重要性的残基

Nagy, Gregory; Diabate, Mariame; Banerjee, Tapahsama; Adamovich, Aleksandra I; Smith, Nahum; Jeon, Hyeongseon; Dhar, Shruti; Liu, Wenfang; Burgess, Katherine; Chung, Dongjun; Starita, Lea M; Parvin, Jeffrey D

The functional impact of BRCA1 BRCT domain variants using multiplexed DNA double-strand break repair assays.

利用多重DNA双链断裂修复试验研究BRCA1 BRCT结构域变异的功能影响

Adamovich Aleksandra I, Diabate Mariame, Banerjee Tapahsama, Nagy Gregory, Smith Nahum, Duncan Kathryn, Mendoza Mendoza Erika, Prida Gisselle, Freitas Michael A, Starita Lea M, Parvin Jeffrey D

A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function

多重同源定向DNA修复分析揭示了1000多种BRCA1错义突变对蛋白质功能的影响

Starita, Lea M; Islam, Muhtadi M; Banerjee, Tapahsama; Adamovich, Aleksandra I; Gullingsrud, Justin; Fields, Stanley; Shendure, Jay; Parvin, Jeffrey D

Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients

整合分析体细胞突变和转录组数据,对乳腺癌患者进行功能分层

Zhang, Jie; Abrams, Zachary; Parvin, Jeffrey D; Huang, Kun

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells

Ran结合蛋白9 (RanBP9) 是肺癌细胞中一种新型的细胞DNA损伤反应介质。

Palmieri, Dario; Scarpa, Mario; Tessari, Anna; Uka, Rexhep; Amari, Foued; Lee, Cindy; Richmond, Timothy; Foray, Claudia; Sheetz, Tyler; Braddom, Ashley; Burd, Christin E; Parvin, Jeffrey D; Ludwig, Thomas; Croce, Carlo M; Coppola, Vincenzo

Patterns and functional implications of rare germline variants across 12 cancer types

12种癌症类型中罕见种系变异的模式和功能意义

Lu, Charles; Xie, Mingchao; Wendl, Michael C; Wang, Jiayin; McLellan, Michael D; Leiserson, Mark D M; Huang, Kuan-Lin; Wyczalkowski, Matthew A; Jayasinghe, Reyka; Banerjee, Tapahsama; Ning, Jie; Tripathi, Piyush; Zhang, Qunyuan; Niu, Beifang; Ye, Kai; Schmidt, Heather K; Fulton, Robert S; McMichael, Joshua F; Batra, Prag; Kandoth, Cyriac; Bharadwaj, Maheetha; Koboldt, Daniel C; Miller, Christopher A; Kanchi, Krishna L; Eldred, James M; Larson, David E; Welch, John S; You, Ming; Ozenberger, Bradley A; Govindan, Ramaswamy; Walter, Matthew J; Ellis, Matthew J; Mardis, Elaine R; Graubert, Timothy A; Dipersio, John F; Ley, Timothy J; Wilson, Richard K; Goodfellow, Paul J; Raphael, Benjamin J; Chen, Feng; Johnson, Kimberly J; Parvin, Jeffrey D; Ding, Li

Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks

BARD1错义变异体在DNA双链断裂同源定向修复中的功能分析

Lee, Cindy; Banerjee, Tapahsama; Gillespie, Jessica; Ceravolo, Amanda; Parvinsmith, Matthew R; Starita, Lea M; Fields, Stanley; Toland, Amanda E; Parvin, Jeffrey D

NUSAP1 influences the DNA damage response by controlling BRCA1 protein levels

NUSAP1通过控制BRCA1蛋白水平影响DNA损伤反应。

Kotian, Shweta; Banerjee, Tapahsama; Lockhart, Ainsley; Huang, Kun; Catalyurek, Umit V; Parvin, Jeffrey D