日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids

在 3D 人类 iPSC 衍生的皮质球体中筛选神经网络活动调节剂

Grace Woodruff, Naomi Phillips, Cassiano Carromeu, Oivin Guicherit, Alistair White, McCay Johnson, Fabian Zanella, Blake Anson, Timothy Lovenberg, Pascal Bonaventure, Anthony W Harrington

GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact

GPR139 和多巴胺 D2 受体在大脑的相同细胞中共同表达并可能在功能上相互作用

Lien Wang, Grace Lee, Chester Kuei, Xiang Yao, Anthony Harrington, Pascal Bonaventure, Timothy W Lovenberg, Changlu Liu

Mutagenesis of GPR139 reveals ways to create gain or loss of function receptors

GPR139 的诱变揭示了获得或丧失功能受体的方法

Lien Wang, Grace Lee, Amy Shih, Chester Kuei, Diane Nepomuceno, Michelle Wennerholm, Frances Fan, Jiejun Wu, Pascal Bonaventure, Timothy W Lovenberg, Changlu Liu

Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro

体外重新评估促肾上腺皮质激素和促黑素细胞激素对GPR139的激活作用

Diane Nepomuceno ,Chester Kuei ,Curt Dvorak ,Timothy Lovenberg ,Changlu Liu ,Pascal Bonaventure

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

Orexin 通过 Orexin 受体 1、磷脂酶 C 和钠钙交换器使中央杏仁核神经元去极化并调节条件性恐惧

Erik T Dustrude, Izabela F Caliman, Cristian S Bernabe, Stephanie D Fitz, Laura A Grafe, Seema Bhatnagar, Pascal Bonaventure, Philip L Johnson, Andrei I Molosh, Anantha Shekhar

Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation

评估新型脑渗透性选择性食欲素 1 受体拮抗剂 JNJ-54717793 在两种惊恐发作诱发大鼠模型中的作用

Pascal Bonaventure, Christine Dugovic, Brock Shireman, Cathy Preville, Sujin Yun, Brian Lord, Diane Nepomuceno, Michelle Wennerholm, Timothy Lovenberg, Nicolas Carruthers, Stephanie D Fitz, Anantha Shekhar, Philip L Johnson

Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model

下丘脑食欲素在手术绝经模型中加剧对焦虑刺激的皮肤血管扩张反应中的作用

Lauren M Federici, Izabela Facco Caliman, Andrei I Molosh, Stephanie D Fitz, William A Truitt, Pascal Bonaventure, Janet S Carpenter, Anantha Shekhar, Philip L Johnson

Direct Imaging of Hippocampal Epileptiform Calcium Motifs Following Kainic Acid Administration in Freely Behaving Mice

自由活动小鼠注射海人酸后海马癫痫样钙基序的直接成像

Tamara K Berdyyeva, E Paxon Frady, Jonathan J Nassi, Leah Aluisio, Yauheniya Cherkas, Stephani Otte, Ryan M Wyatt, Christine Dugovic, Kunal K Ghosh, Mark J Schnitzer, Timothy Lovenberg, Pascal Bonaventure

Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor

甘氨酸苯甲酰胺作为 GPR139 受体强效激动剂的鉴定和 SAR

Curt A Dvorak, Heather Coate, Diane Nepomuceno, Michelle Wennerholm, Chester Kuei, Brian Lord, David Woody, Pascal Bonaventure, Changlu Liu, Timothy Lovenberg, Nicholas I Carruthers

Zolpidem reduces hippocampal neuronal activity in freely behaving mice: a large scale calcium imaging study with miniaturized fluorescence microscope

唑吡坦降低自由活动小鼠的海马神经元活动:利用微型荧光显微镜进行的大规模钙成像研究

Tamara Berdyyeva, Stephani Otte, Leah Aluisio, Yaniv Ziv, Laurie D Burns, Christine Dugovic, Sujin Yun, Kunal K Ghosh, Mark J Schnitzer, Timothy Lovenberg, Pascal Bonaventure