Altered splicing of ATG16-L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non-small cell lung cancer
ATG16-L1 剪接异常通过阻断自噬介导非小细胞肺癌对 EGFR 酪氨酸激酶抑制剂的获得性耐药
期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.13229
Hatat, Anne-Sophie; Benoit-Pilven, Clara; Pucciarelli, Amélie; de Fraipont, Florence; Lamothe, Lucie; Perron, Pascal; Rey, Amandine; Levra, Matteo Giaj; Toffart, Anne-Claire; Auboeuf, Didier; Eymin, Beatrice; Gazzeri, Sylvie
肺癌
肿瘤
肿瘤免疫
信号转导
EGF
EGFR
细胞生物学
自噬
