日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcriptomics profiling of the non-small cell lung cancer microenvironment across disease stages reveals dual immune cell-type behaviors

非小细胞肺癌微环境在不同疾病阶段的转录组学分析揭示了双重免疫细胞类型行为

Marcelo Hurtado # ,Leila Khajavi # ,Abdelmounim Essabbar ,Michael Kammer ,Ting Xie ,Alexis Coullomb ,Anne Pradines ,Anne Casanova ,Anna Kruczynski ,Sandrine Gouin ,Estelle Clermont ,Léa Boutillet ,Maria Fernanda Senosain ,Yong Zou ,Shillin Zhao # ,Prosper Burq ,Abderrahim Mahfoudi ,Jerome Besse ,Pierre Launay ,Alexandre Passioukov ,Eric Chetaille ,Gilles Favre ,Fabien Maldonado ,Francisco Cruzalegui ,Olivier Delfour ,Julien Mazières ,Vera Pancaldi

Systemic immune response to a CD40 agonist antibody in nonhuman primates

非人灵长类动物对 CD40 激动剂抗体的系统性免疫反应

Caudell, David L; Dugan, Gregory O; Babitzki, Galina; Schubert, Christine; Braendli-Baiocco, Annamaria; Wasserman, Ken; Acona, Gonzalo; Stern, Martin; Passioukov, Alexandre; Cline, J Mark; Charo, Jehad

An exploratory, open-label, randomized, multicenter study to investigate the pharmacodynamics of a glycoengineered antibody (imgatuzumab) and cetuximab in patients with operable head and neck squamous cell carcinoma

一项探索性、开放标签、随机、多中心研究,旨在研究糖基化抗体(imgatuzumab)和西妥昔单抗在可手术头颈部鳞状细胞癌患者中的药效学。

Temam, S; Spicer, J; Farzaneh, F; Soria, J C; Oppenheim, D; McGurk, M; Hollebecque, A; Sarini, J; Hussain, K; Soehrman Brossard, S; Manenti, L; Evers, S; Delmar, P; Di Scala, L; Mancao, C; Feuerhake, F; Andries, L; Ott, M G; Passioukov, A; Delord, J P

Glyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy

糖基化改造的抗EGFR单克隆抗体可诱导结直肠癌患者NK细胞产生抗体依赖性细胞毒性作用(ADCC),且不受化疗影响。

Oppenheim, D E; Spreafico, R; Etuk, A; Malone, D; Amofah, E; Peña-Murillo, C; Murray, T; McLaughlin, L; Choi, B S; Allan, S; Belousov, A; Passioukov, A; Gerdes, C; Umaña, P; Farzaneh, F; Ross, P