The SWI/SNF ATPase BRG1 stimulates DNA end resection and homologous recombination by reducing nucleosome density at DNA double strand breaks and by promoting the recruitment of the CtIP nuclease.
SWI/SNF ATPase BRG1 通过降低 DNA 双链断裂处的核小体密度和促进 CtIP 核酸酶的募集来刺激 DNA 末端切除和同源重组
期刊:Cell Cycle
影响因子:3.4
doi:10.1080/15384101.2020.1831256
Hays Emily, Nettleton Elizabeth, Carter Caitlin, Morales Mariangel, Vo Lynn, Passo Max, Vélez-Cruz Renier
