日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GIPR signaling modulates PYY-induced hypophagia and malaise in rodents

GIPR信号通路调节啮齿动物中PYY诱导的食欲减退和不适感

Borner, Tito; Pataro, Allison M; Curtis, Genevieve R; Alonso, Brandon; Hu, Jiayin; Fortin, Samantha M; Koul-Tiwari, Richa; Hughes, Emily; Kong, Jimmy X; Jordan, Emily; Barnes, Robert; Bernardo, Barbara; Gardner, Maxwell; Ma, Wenzhe; Gosset, James R; Esquejo, Ryan M; Fortin, Jean-Philippe; De Jonghe, Bart C; Bence, Kendra K; Hayes, Matthew R

GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian models

在临床前哺乳动物模型中,GLP-1R 偏向性 cAMP 激动剂作用可维持血糖控制,并减少不适和呕吐。

Baumer-Harrison, Caitlin; Aldaghma, Danya; White, Alex D; Applebey, Sarah V; Pataro, Allison M; Mohiby, Allaha Z; Alonso, Brandon; Xiao, Allison G; O'Farrell, Libbey S; Qian, Yuewei; Coskun, Tamer; Coghlan, Matthew P; Willard, Francis S; Ai, Minrong; Sloop, Kyle W; Doyle, Robert P; Borner, Tito; De Jonghe, Bart C; Hayes, Matthew R

Hypophagia and body weight loss by tirzepatide are accompanied by fewer GI adverse events compared to semaglutide in preclinical models.

在临床前模型中,与司美格鲁肽相比,替拉帕肽引起的食欲减退和体重减轻伴随的胃肠道不良事件较少

Borner Tito, Pataro Allison M, Doebley Sarah A, Furst Charles D, White Alex D, Gao Serena X, Chow Angela, Sanchez-Navarro Marcos J, Ghidewon Misgana Y, Halas Julia G, Mohiby Allaha Z, Willard Francis S, Grill Harvey J, Ai Minrong, Samms Ricardo J, Hayes Matthew R, De Jonghe Bart C

Central mechanisms of emesis: A role for GDF15

呕吐的中枢机制:GDF15 的作用

Borner, Tito; Pataro, Allison M; De Jonghe, Bart C