日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of the aryl hydrocarbon receptor promotes cancer cell resistance to BRAFV600E targeted therapies

芳烃受体的缺失会促进癌细胞对BRAFV600E靶向治疗产生耐药性

Zerfaoui, Mourad; Patel, Dharmeshkumar; Zhang, Yueqi; Schinazi, Raymond F; Errami, Youssef

Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents

新型二聚体衣壳组装调节剂作为一类独特的高效抗乙肝病毒药物

Amblard, Franck; Chen, Zhe; Kra, Kalouna; Patel, Dharmeshkumar; Bassit, Leda; Gargowitsch, Laetitia; Degrouard, Jéril; Rat, Virgile; Arteni, Ana-Andreea; Matthews, Lauren; Ravichandran, Shreya M; Jiang, Alfred; Athanasiadis, Antonis; Dangas, Georgios; Abate, Maedot; Tresset, Guillaume; Pronost, Julien; Salman, Mohammad; Verma, Kiran; Kirby, Karen A; Michailidis, Eleftherios; Rocquigny, Hugues de; Durantel, David; Bressanelli, Stéphane; Sarafianos, Stefan G; Schinazi, Raymond F

Combating yellow fever virus with 7-deaza-7-fluoro-2'-C-methyladenosine

用7-脱氮-7-氟-2'-C-甲基腺苷对抗黄热病毒

LeCher, Julia C; Costa, Vivian Vasconcelos; Rust, Lauren N; Bassit, Leda C; Patel, Dharmeshkumar; Rezaei, Sahar; Moua, Justin; Santos, Felipe Rocha da Silva; Goncalves, Matheus Rodrigues; Queroz-Junior, Celso Martins; Marim, Fernanda Martins; Zhou, Longhu; Lee, Sujin; McBrayer, Tamara; De, Ramyani; Azadi, Niloufar; Salman, Mohammad; Zandi, Keivan; Amblard, Franck; Burwitz, Benjamin; Teixeira, Mauro M; Schinazi, Raymond F

Discovery of broad-spectrum antivirals targeting viral proteases using in silico structural modeling and cellular analysis

利用计算机结构建模和细胞分析发现靶向病毒蛋白酶的广谱抗病毒药物

Patel, Dharmeshkumar; De, Ramyani; Azadi, Niloufar; Lee, Sujin; Shooter, Savannah; Amichai, Sarah; Zhou, Shaoman; Monroe, Danielle; Mahanke, Cameron; McBrayer, Tamara R; Muczynski, Michael; Al-Homoudi, Abdullah; Engel, Joseph; Bochkov, Yury A; Gern, James E; Kovari, Ladislau C; Amblard, Franck; Schinazi, Raymond F

Rapid visual detection of tick borne Anaplasma marginale in Indian buffaloes using loop mediated isothermal amplification assay targeting major surface protein 5 gene

利用靶向主要表面蛋白5基因的环介导等温扩增检测法,快速可视化检测印度水牛体内蜱传边缘无形体病。

Kumar, Niranjan; Solanki, Jayesh Babulal; Patel, Dharmeshkumar Chandrakantbhai

Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.

冠状病毒3C样蛋白酶新型肽模拟抑制剂的合成及生物学评价

Amblard Franck, LeCher Julia C, De Ramyani, Zhou Shaoman, Liu Peng, Goh Shu Ling, Tao Sijia, Patel Dharmeshkumar, Downs-Bowen Jessica, Zandi Keivan, Zhang Huanchun, Chaudhry Gitika, McBrayer Tamara, Muczynski Michael, Al-Homoudi Abdullah, Engel Joseph, Lan Shuiyun, Sarafianos Stefan G, Kovari Ladislau C, Schinazi Raymond F

Sustained antiviral insulin signaling during West Nile virus infection results in viral mutations.

西尼罗河病毒感染期间持续的抗病毒胰岛素信号传导会导致病毒突变

Char Aditya B, Trammell Chasity E, Fawcett Stephen, Chauhan Manish, Debebe Yared, Céspedes Nora, Paslay Ryder A, Ahlers Laura R H, Patel Dharmeshkumar, Luckhart Shirley, Goodman Alan G

Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers

生物物理学指导的乙型肝炎病毒衣壳组装调节剂先导化合物发现

Fan, Zixing; Pavlova, Anna; Jenkins, Matthew C; Bassit, Leda; Salman, Mohammad; Lynch, Diane L; Patel, Dharmeshkumar; Korablyov, Maksym; Finn, M G; Schinazi, Raymond F; Gumbart, James C

The premise of capsid assembly modulators towards eliminating HBV persistence

利用衣壳组装调节剂消除乙型肝炎病毒持续感染的前提

Bassit, Leda; Amblard, Franck; Patel, Dharmeshkumar; Biteau, Nicolas; Chen, Zhe; Kasthuri, Mahesh; Zhou, Shaoman; Schinazi, Raymond F

Synthesis and evaluation of highly potent HBV capsid assembly modulators (CAMs)

高效乙型肝炎病毒衣壳组装调节剂(CAMs)的合成与评价

Amblard, Franck; Chen, Zhe; Wiseman, John; Zhou, Shaoman; Liu, Peng; Salman, Mohammad; Verma, Kiran; Azadi, Niloufar; Downs-Bowen, Jessica; Tao, Sijia; Kumari, Amita; Zhang, Qingling; Smith, David B; Patel, Dharmeshkumar; Bassit, Leda; Schinazi, Raymond F