日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma

非嗜酸性哮喘中炎症诱导的表达CFTR的气道离子细胞丢失

Chen, Ling; A Hoefel, Gabriela; Pathinayake, Prabuddha S; Reid, Andrew; Pillar, Amber L; Kelly, Coady; Tan, HuiYing; Ali, Ayesha; Kim, Richard Y; Hansbro, Philip M; Brody, Steven L; Foster, Paul S; Horvat, Jay C; Riveros, Carlos; Awatade, Nikhil; Wark, Peter A B; Kaiko, Gerard E

Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a bronchoscopy endobronchial biopsy study.

上皮间质转化是哮喘-COPD重叠患者大气道中一个活跃的过程,吸入皮质类固醇治疗可部分消除这一过程:支气管镜内支气管活检研究

Dey Surajit, Lu Wenying, Pathinayake Prabuddha S, Waters Maddison, Haug Greg, Larby Josie, Weber Heinrich C, Wark Peter A B, Eapen Mathew Suji, Sohal Sukhwinder Singh

Endoplasmic reticulum stress enhances the expression of TLR3-induced TSLP by airway epithelium

内质网应激增强气道上皮细胞中TLR3诱导的TSLP的表达。

Pathinayake, Prabuddha S; Hsu, Alan C-Y; Nichol, Kristy S; Horvat, Jay C; Hansbro, Philip M; Wark, Peter A B

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi

利用慢性阻塞性肺病类器官研究宿主-病原体相互作用揭示了SARS-CoV-2在支气管中增强的病毒适应性

Chan, Louisa L Y; Anderson, Danielle E; Cheng, Hong Sheng; Ivan, Fransiskus Xaverius; Chen, Si; Kang, Adrian E Z; Foo, Randy; Gamage, Akshamal M; Tiew, Pei Yee; Koh, Mariko Siyue; Lee, Ken Cheah Hooi; Nichol, Kristy; Pathinayake, Prabuddha S; Chan, Yik Lung; Yeo, Tsin Wen; Oliver, Brian G; Wark, Peter A B; Liu, Linbo; Tan, Nguan Soon; Wang, Lin-Fa; Chotirmall, Sanjay H

Asthma, COPD and SARS-CoV-2 infection (COVID-19): potential mechanistic insights

哮喘、慢性阻塞性肺病和SARS-CoV-2感染(COVID-19):潜在的机制见解

Wark, Peter A B; Pathinayake, Prabuddha S; Eapen, Mathew Suji; Sohal, Sukhwinder Singh

ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma

ACE2在老年人和健康男性的气道上皮细胞中表达升高,但在哮喘患者中表达降低。

Wark, Peter A B; Pathinayake, Prabuddha S; Kaiko, Gerard; Nichol, Kristy; Ali, Ayesha; Chen, Ling; Sutanto, Erika N; Garratt, Luke W; Sohal, Sukhwinder S; Lu, Wenying; Eapen, Mathew S; Oldmeadow, Christopher; Bartlett, Nathan; Reid, Andrew; Veerati, Punnam; Hsu, Alan C-Y; Looi, Kevin; Iosifidis, Thomas; Stick, Stephen M; Hansbro, Philip M; Kicic, Anthony

The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders

内质网应激与NLRP3炎症小体之间复杂的相互作用:炎症性疾病的潜在治疗靶点

Chong, Wai Chin; Shastri, Madhur D; Peterson, Gregory M; Patel, Rahul P; Pathinayake, Prabuddha S; Dua, Kamal; Hansbro, Nicole G; Hsu, Alan C; Wark, Peter A; Shukla, Shakti Dhar; Johansen, Matt D; Schroder, Kate; Hansbro, Philip M

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis

特发性肺纤维化病理学中的成纤维细胞衰老

Waters, David W; Blokland, Kaj E C; Pathinayake, Prabuddha S; Burgess, Janette K; Mutsaers, Steven E; Prele, Cecilia M; Schuliga, Michael; Grainge, Christopher L; Knight, Darryl A