日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1

表观遗传读取器,含溴结构域 2,通过与 ETS 原癌基因 1 相互作用介导胆管细胞衰老

Jeong-Han Kang, Patrick L Splinter, Christy E Trussoni, Nicholas E Pirius, Gregory J Gores, Nicholas F LaRusso, Steven P O'Hara

Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor

衰老的胆管细胞释放细胞外囊泡,通过表皮生长因子受体改变靶细胞表型

Mohammed S Al Suraih, Christy E Trussoni, Patrick L Splinter, Nicholas F LaRusso, Steven P O'Hara

The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1

转录因子 ETS1 通过表观遗传上调凋亡抑制因子 BCL2L1 促进衰老胆管细胞的抗凋亡能力

Steven P O'Hara, Patrick L Splinter, Christy E Trussoni, Maria Eugenia Guicciardi, Noah P Splinter, Mohammed S Al Suraih, Navine Nasser-Ghodsi, Deborah Stollenwerk, Gregory J Gores, Nicholas F LaRusso

ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A

ETS 原癌基因 1 转录上调胆管细胞衰老相关蛋白细胞周期蛋白依赖性激酶抑制剂 2A

Steven P O'Hara, Patrick L Splinter, Christy E Trussoni, Maria J Lorenzo Pisarello, Lorena Loarca, Noah S Splinter, Bryce F Schutte, Nicholas F LaRusso

Lipopolysaccharide (LPS)-Induced Biliary Epithelial Cell NRas Activation Requires Epidermal Growth Factor Receptor (EGFR)

脂多糖 (LPS) 诱导的胆道上皮细胞 NRas 激活需要表皮生长因子受体 (EGFR)

Christy E Trussoni, James H Tabibian, Patrick L Splinter, Steven P O'Hara

Centrosomal abnormalities characterize human and rodent cystic cholangiocytes and are associated with Cdc25A overexpression

中心体异常是人类和啮齿动物囊性胆管细胞的特征,与 Cdc25A 过度表达有关

Tatyana V Masyuk, Seung-Ok Lee, Brynn N Radtke, Angela J Stroope, Bing Huang, Jesús M Banales, Anatoliy I Masyuk, Patrick L Splinter, Sergio A Gradilone, Gabriella B Gajdos, Nicholas F LaRusso

Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

TGR5 的纤毛亚细胞定位决定了胆管细胞对胆汁酸信号的功能反应

Anatoliy I Masyuk, Bing Q Huang, Brynn N Radtke, Gabriella B Gajdos, Patrick L Splinter, Tatyana V Masyuk, Sergio A Gradilone, Nicholas F LaRusso

Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD

Trpv4 的激活可降低 ARPKD 动物模型中囊性胆管细胞的过度增殖表型

Sergio A Gradilone, Tatyana V Masyuk, Bing Q Huang, Jesus M Banales, Guillermo L Lehmann, Brynn N Radtke, Angela Stroope, Anatoliy I Masyuk, Patrick L Splinter, Nicholas F LaRusso

Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis

永生化肝内皮细胞:用于研究运动和血管生成的细胞培养模型

Robert C Huebert, Kumaravelu Jagavelu, Ann F Liebl, Bing Q Huang, Patrick L Splinter, Nicholas F LaRusso, Raul A Urrutia, Vijay H Shah

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia

胆汁外泌体通过与初级纤毛相互作用影响胆管细胞的调节机制和增殖

Anatoliy I Masyuk, Bing Q Huang, Christopher J Ward, Sergio A Gradilone, Jesus M Banales, Tatyana V Masyuk, Brynn Radtke, Patrick L Splinter, Nicholas F LaRusso