日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrated multi-omic atlas reveals the hierarchy of spatiotemporal regulatory networks of mouse gastrulation.

整合多组学图谱揭示了小鼠原肠胚形成时空调控网络的层级结构。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68291-w
Yang Xianfa, Xie Bingbing, Shen Penglei, Chen Yingying, Li Chunjie, Tan Fengxiang, Yang Yumeng, Yang Yun, Song Rui, Mi Panpan, Liu Zhiwen, Wen Mingzhu, Tam Patrick P L, Suo Shengbao, Jing Naihe
信号转导
发表日期：2026
文献求助 收藏

Neural crest cell-derived DKK1 and NEDD4 modulate Wnt signalling in the second heart field to orchestrate outflow tract development.

神经嵴细胞衍生的 DKK1 和 NEDD4 调节第二心场中的 Wnt 信号传导，从而协调流出道的发育。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68459-4
Wiszniak Sophie, Alankarage Dimuthu, Lohraseb Iman, Marchant Ceilidh, Secker Genevieve, Domingo Deepti, Hartmann Jasmine, Zhang Tianyang, Parker Wendy, Toubia John, White Melissa, Piltz Sandra, Tondl Markus, Giannoulatou Eleni, Winlaw David, Blue Gillian M, Tam Patrick P L, Thomas Paul, Harvey Natasha, Dunwoodie Sally L, Schwarz Quenten
DKK1
发育与干细胞
信号转导
Wnt/β-Catenin
细胞生物学
NEDD4
发表日期：2026
文献求助 收藏

Pyroxd1 is essential for murine viability with the homozygous N155S recurrent variant linked to myopathy, muscle hypotrophy and osteopenia.

Pyroxd1 对小鼠的生存至关重要，纯合 N155S 复发性变异与肌病、肌肉萎缩和骨质减少有关。

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-026-02259-1
Evesson Frances J, Dziaduch Gregory, Yasa Joe, Best Heather A, Kiriaev Leonit, Pang Ignatius, Jones Vanessa, Kettle Emma, Zhang Katharine, Piper Ann-Katrin, Wark Jesse R, Scott Isaac, Joshi Himanshu, Sutton R Bryan, Tam Patrick P L, Houweling Peter J, Graham Mark E, Yuen Michaela, Lemcket Frances A, Cooper Sandra T
发表日期：2026
文献求助 收藏

Constructing the spatiotemporal atlas of single-cell lineage trajectories in stereotypic biological structures

构建典型生物结构中单细胞谱系轨迹的时空图谱

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114307
Wang, Ran; Yang, Xianfa; Lian, Chengfei; Wang, Jianjie; Chen, Jiehui; Qian, Yun; Xu, Yaochen; Wang, Liantang; Marioni, John C; Tam, Patrick P L; Jing, Naihe
细胞生物学
单细胞
发表日期：2026
文献求助 收藏

Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure

多系干细胞分化图谱揭示TMEM88是血压发育的调节因子

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-56533-2
Sophie Shen ，Tessa Werner ，Samuel W Lukowski ，Stacey Andersen ，Yuliangzi Sun ，Woo Jun Shim ，Dalia Mizikovsky ，Sakurako Kobayashi ，Jennifer Outhwaite ，Han Sheng Chiu ，Xiaoli Chen ，Gavin Chapman ，Ella M M A Martin ，Di Xia ，Duy Pham ，Zezhuo Su ，Daniel Kim ，Pengyi Yang ，Men Chee Tan ，Enakshi Sinniah ，Qiongyi Zhao ，Sumedha Negi ，Meredith A Redd ，Joseph E Powell ，Sally L Dunwoodie ，Patrick P L Tam ，Mikael Bodén ，Joshua W K Ho ，Quan Nguyen ，Nathan J Palpant
细胞生物学
干细胞
发育与干细胞
发表日期：2025
文献求助 收藏

Procollagen IIA mediates positive feedback control of the mouse cardiogenic transcriptional network

IIA型前胶原介导小鼠心肌生成转录网络的正反馈控制

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2422592122
Leung, Alan W; Wong, Sandra Y; Zhang, Janet C; Leung, Keith K H; Dung, Nelson W F; Shang, Catherine A; Prall, Owen W; Nim, Hieu T; See, Michael; Ramialison, Mirana; Chan, Danny; Mohun, Timothy J; Harvey, Richard P; Tam, Patrick P L; Cheah, Kathryn S E
发表日期：2025
文献求助 收藏

MIXL1 activation in endoderm differentiation of human induced pluripotent stem cells

MIXL1在人诱导多能干细胞内胚层分化中的激活

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2025.102482
Osteil, Pierre; Withey, Sarah; Santucci, Nicole; Aryamanesh, Nader; Pang, Ignatius; Salehin, Nazmus; Sun, Jane; Qin, Annie; Su, Jiayi; Knowles, Hilary; Li, Xiucheng Bella; Cai, Simon; Wolvetang, Ernst; Tam, Patrick P L
细胞生物学
发育与干细胞
干细胞
发表日期：2025
文献求助 收藏

Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells

抑制Nodal信号通路活性会促进外胚层干细胞向外胚层分化

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2025.102609
Liu, Chang; Wang, Ran; He, Zhisong; Osteil, Pierre; Wilkie, Emilie; Yang, Xianfa; Chen, Jun; Cui, Guizhong; Guo, Wenke; Chen, Yingying; Peng, Guangdun; Tam, Patrick P L; Jing, Naihe
信号转导
细胞生物学
发育与干细胞
干细胞
发表日期：2025
文献求助 收藏

Pluripotent cell states and fates in human embryo models

人类胚胎模型中的多能细胞状态和命运

期刊:Development
影响因子:3.6
doi:10.1242/dev.204565
Sozen, Berna; Tam, Patrick P L; Pera, Martin F
细胞生物学
发表日期：2025
文献求助 收藏

Stem cell-based embryo models: The 2021 ISSCR stem cell guidelines revisited

基于干细胞的胚胎模型：2021年ISSCR干细胞指南再探

期刊:Stem Cell Reports
影响因子:
doi:10.1016/j.stemcr.2025.102514
Clark, Amander T; Cook-Andersen, Heidi; Franklin, Sarah; Isasi, Rosario; Mathews, Debra J H; Pasque, Vincent; Rugg-Gunn, Peter J; Tam, Patrick P L; Wang, Hongmei; Zylicz, Jan J; Rossant, Janet
细胞生物学
发育与干细胞
干细胞
发表日期：2025
文献求助 收藏