Poly (I:C) Exposure in Early Life Alters Methylation of DNA and Acetylation of Histone at Synaptic Plasticity Gene Promoter in Developing Rat Brain Leading to Memory Impairment
早期接触聚肌苷酸胞苷酸(Poly (I:C))会改变发育中大鼠脑突触可塑性基因启动子处的DNA甲基化和组蛋白乙酰化,从而导致记忆障碍。
期刊:Annals of Neurosciences
影响因子:2.4
doi:10.1177/0972753120919704
Baghel, Meghraj Singh; Singh, Brijendra; Patro, Nisha; Khanna, Vinay Kumar; Patro, Ishan Kumar; Thakur, Mahendra Kumar
表观遗传
DNA甲基化
Rat
神经科学
乙酰化
DNA甲基化
发育与干细胞