日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hepatic adaptation to chronic metabolic stress primes tumorigenesis.

肝脏对慢性代谢应激的适应会促进肿瘤发生。

Tzouanas Constantine N, Shay Jessica E S, Sherman Marc S, Rubin Adam J, Mead Benjamin E, Dao Tyler T, Tao Junyan, Lehrich Brandon M, Eng George, Patterson-Fortin Jeffrey, Butzlaff Titus, Mana Miyeko D, Kolb Kellie E, Walesky Chad, Pepe-Mooney Brian J, Smith Colton J, Prakadan Sanjay M, Ramseier Michelle L, Tong Yuzhou Evelyn, Joung Julia, Chi Fangtao, McMahon-Skates Thomas, Winston Carolyn L, Jeong Woo-Jeong, Aney Katherine J, Chen Ethan, Nissim Sahar, Zhang Feng, Deshpande Vikram, Monga Satdarshan P, Lauer Georg M, Goessling Wolfram, Yilmaz Ömer H, Shalek Alex K

A rare case report on esophageal squamous cell carcinoma metastatic to the pancreas

一例罕见的食管鳞状细胞癌转移至胰腺的病例报告

Bhatti, Inderpreet; Rogers, Robert E; Witt, Benjamin L; Nevala-Plagemann, Chris; Patterson-Fortin, Jeffrey

53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer

53BP1 缺失在卵巢癌和胰腺癌中引发 cGAS-STING 依赖性抗肿瘤免疫

Yajie Sun #, Jeffrey Patterson-Fortin #, Sen Han, Zhe Li, Zuzanna Nowicka, Yuna Hirohashi, Susan Kilgas, Jae Kyo Yi, Alexander Spektor, Wojciech Fendler, Panagiotis A Konstantinopoulos, Dipanjan Chowdhury

Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity

新生霉素阻断核酸与 Polθ 结合并抑制其 ATPase 活性的刺激

Aleem Syed, Frantisek Filandr, Jeffrey Patterson-Fortin, Albino Bacolla, Ramya Ravindranathan, Jia Zhou, Drew T McDonald, Mohammed E Albuhluli, Amy Verway-Cohen, Joseph A Newman, Miaw-Sheue Tsai, Darin E Jones, David C Schriemer, Alan D D'Andrea, John A Tainer

Retraction Note: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

撤稿声明:聚合酶θ抑制剂可激活cGAS-STING通路,并在BRCA缺陷型癌症模型中与免疫检查点阻断剂协同作用。

Patterson-Fortin, Jeffrey; Jadhav, Heta; Pantelidou, Constantia; Phan, Tin; Grochala, Carter; Mehta, Anita K; Guerriero, Jennifer L; Wulf, Gerburg M; Wolpin, Brian M; Stanger, Ben Z; Aguirre, Andrew J; Cleary, James M; D'Andrea, Alan D; Shapiro, Geoffrey I

Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

聚合酶θ抑制可激活cGAS-STING通路并与BRCA缺陷癌症模型中的免疫检查点阻断协同作用

Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D D'Andrea, Geoffrey I Shapiro

Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers

靶向 DNA 修复并联合抑制 NHEJ 和 MMEJ 可在 TP53 突变癌症中诱导合成致死率

Jeffrey Patterson-Fortin, Arindam Bose, Wei-Chih Tsai, Carter Grochala, Huy Nguyen, Jia Zhou, Kalindi Parmar, Jean-Bernard Lazaro, Joyce Liu, Kelsey McQueen, Geoffrey I Shapiro, David Kozono, Alan D D'Andrea

In vitro efficacy of a copper iodine complex PPE disinfectant for SARS-CoV-2 inactivation

体外铜碘复合物PPE消毒剂对SARS-CoV-2灭活的功效

Mantlo, Emily; Rhodes, Tanya; Boutros, Jenny; Patterson-Fortin, Laura; Evans, Alex; Paessler, Slobodan

Anti-TNF therapy-induced lupus erythematosus-like syndrome in a patient treated with adalimumab for cutaneous psoriasis

接受阿达木单抗治疗皮肤银屑病的患者出现抗TNF疗法诱发的红斑狼疮样综合征

Stein, Julie E; Patterson-Fortin, Jeffrey; Bodnar, Benjamin E

Neptune: a bioinformatics tool for rapid discovery of genomic variation in bacterial populations

Neptune:一种用于快速发现细菌群体基因组变异的生物信息学工具

Marinier, Eric; Zaheer, Rahat; Berry, Chrystal; Weedmark, Kelly A; Domaratzki, Michael; Mabon, Philip; Knox, Natalie C; Reimer, Aleisha R; Graham, Morag R; Chui, Linda; Patterson-Fortin, Laura; Zhang, Jian; Pagotto, Franco; Farber, Jeff; Mahony, Jim; Seyer, Karine; Bekal, Sadjia; Tremblay, Cécile; Isaac-Renton, Judy; Prystajecky, Natalie; Chen, Jessica; Slade, Peter; Van Domselaar, Gary