MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib.
MYC 和 EGR1 协同作用,通过控制 NOXA 和 BIM 转录,在用蛋白酶体抑制剂硼替佐米治疗时触发肿瘤细胞死亡
期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gku763
Wirth Matthias, Stojanovic Natasa, Christian Jan, Paul Mariel C, Stauber Roland H, Schmid Roland M, Häcker Georg, Krämer Oliver H, Saur Dieter, Schneider Günter