日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Frontal cortex pyramidal neuron expression profiles differentiate the prodromal stage from progressive degeneration across the Alzheimer's disease spectrum

额叶皮层锥体神经元表达谱能够区分阿尔茨海默病谱系中的前驱期和进行性退行性变阶段。

Amanda Labuza,Melissa J Alldred,Harshitha Pidikiti,Michael H Malek-Ahmadi,Sang Han Lee,Adriana Heguy,Paul D Coleman,Souparna Chakrabarty,Gabriela Chiosis,Elliott J Mufson,Stephen D Ginsberg

Intracellular Amyloid-β Detection from Human Brain Sections Using a Microfluidic Immunoassay in Tandem with MALDI-MS

使用微流控免疫分析结合 MALDI-MS 检测人脑切片中的细胞内淀粉样蛋白-β

Jorvani Cruz Villarreal, Keegan Kow, Brian Pham, Ana Egatz-Gomez, Todd R Sandrin, Paul D Coleman, Alexandra Ros

Highly Sensitive and Multiplexed Protein Imaging With Cleavable Fluorescent Tyramide Reveals Human Neuronal Heterogeneity

利用可裂解荧光酪胺进行高灵敏度、多路复用蛋白质成像,揭示人类神经元异质性

Renjie Liao, Manas Mondal, Christopher D Nazaroff, Diego Mastroeni, Paul D Coleman, Joshua Labaer, Jia Guo

Cell death and survival pathways in Alzheimer's disease: an integrative hypothesis testing approach utilizing -omic data sets

阿尔茨海默病中的细胞死亡和存活途径:利用组学数据集的综合假设检验方法

Danielle L Brokaw, Ignazio S Piras, Diego Mastroeni, Daniel J Weisenberger, Jennifer Nolz, Elaine Delvaux, Geidy E Serrano, Thomas G Beach, Matthew J Huentelman, Paul D Coleman

AmpliSeq Transcriptome of Laser Captured Neurons from Alzheimer Brain: Comparison of Single Cell Versus Neuron Pools

AmpliSeq 激光捕获阿尔茨海默病患者大脑神经元转录组:单细胞与神经元池的比较

Wenjun Deng, Changhong Xing, Rob David, Diego Mastroeni, MingMing Ning, Eng H Lo, Paul D Coleman

Novel method to ascertain chromatin accessibility at specific genomic loci from frozen brain homogenates and laser capture microdissected defined cells

从冷冻脑匀浆和激光捕获显微切割确定细胞中特定基因组位点染色质可及性的新方法

Elaine Delvaux, Diego Mastroeni, Jennifer Nolz, Paul D Coleman

Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function

新型抗氧化剂保护线粒体免受低聚淀粉样β蛋白的影响,并有助于维持表观基因组功能

Diego Mastroeni, Omar M Khdour, Pablo M Arce, Sidney M Hecht, Paul D Coleman

Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease

H3k4me3 的异常细胞内定位证实了阿尔茨海默病中的早期表观遗传现象

Diego Mastroeni, Elaine Delvaux, Jennifer Nolz, Yuyan Tan, Andrew Grover, Salvatore Oddo, Paul D Coleman

Reduced RAN expression and disrupted transport between cytoplasm and nucleus; a key event in Alzheimer's disease pathophysiology

RAN 表达减少,细胞质和细胞核之间的运输中断;这是阿尔茨海默病病理生理学中的关键事件

Diego Mastroeni, Leonidas Chouliaras, Andrew Grover, Winnie S Liang, Kevin Hauns, Joseph Rogers, Paul D Coleman

Epigenetic changes in Alzheimer's disease: decrements in DNA methylation

阿尔茨海默病的表观遗传变化:DNA甲基化减少

Diego Mastroeni, Andrew Grover, Elaine Delvaux, Charisse Whiteside, Paul D Coleman, Joseph Rogers