Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models
在人源小鼠肿瘤模型中，靶向 p53 缺陷型三阴性乳腺癌中的 Chk1 具有治疗益处。
期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI79606
Malhotra, Deepti; Thimmulappa, Rajesh K; Mercado, Nicolas; Ito, Kazuhiro; Kombairaju, Ponvijay; Kumar, Sarvesh; Ma, Jinfang; Feller-Kopman, David; Wise, Robert; Barnes, Peter; Biswal, Shyam; D’Apolito, Maria; Du, Xueliang; Zong, Haihong; Catucci, Alessandra; Maiuri, Luigi; Trivisano, Tiziana; Pettoello-Mantovani, Massimo; Campanozzi, Angelo; Raia, Valeria; Pessin, Jeffrey E; Brownlee, Michael; Giardino, Ida; Roccaro, Aldo M; Sacco, Antonio; Maiso, Patricia; Azab, Abdel Kareem; Tai, Yu-Tzu; Reagan, Michaela; Azab, Feda; Flores, Ludmila M; Campigotto, Federico; Weller, Edie; Anderson, Kenneth C; Scadden, David T; Ghobrial, Irene M; Goyama, Susumu; Schibler, Janet; Cunningham, Lea; Zhang, Yue; Rao, Yalan; Nishimoto, Nahoko; Nakagawa, Masahiro; Olsson, Andre; Wunderlich, Mark; Link, Kevin A; Mizukawa, Benjamin; Grimes, H Leighton; Kurokawa, Mineo; Liu, P Paul; Huang, Gang; Mulloy, James C; Abuzeid, Waleed M; Jiang, Xiaoling; Shi, Guoli; Wang, Hui; Paulson, David; Araki, Koji; Jungreis, David; Carney, James; O’Malley, Bert W Jr; Li, Daqing; Ma, Cynthia X; Cai, Shirong; Li, Shunqiang; Ryan, Christine E; Guo, Zhanfang; Schaiff, W Timothy; Lin, Li; Hoog, Jeremy; Goiffon, Reece J; Prat, Aleix; Aft, Rebecca L; Ellis, Matthew J; Piwnica-Worms, Helen
