日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibody-derived in vivo imaging of tau pathology

抗体衍生的 tau 病理体内成像

Senthilkumar Krishnaswamy, Yan Lin, Wajitha J Rajamohamedsait, Hameetha B Rajamohamedsait, Pavan Krishnamurthy, Einar M Sigurdsson

Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments

Tau 病理导致 GABA 能中间神经元丢失,从而导致突触可塑性改变和行为障碍

Josien Levenga, Pavan Krishnamurthy, Hameetha Rajamohamedsait, Helen Wong, Thomas F Franke, Peter Cain, Einar M Sigurdsson, Charles A Hoeffer

Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo

麻醉诱导的过度磷酸化使 3 重复 tau 从微管中分离,而不会影响其在体内的稳定性

Emmanuel Planel, Pavan Krishnamurthy, Tomohiro Miyasaka, Li Liu, Mathieu Herman, Asok Kumar, Alexis Bretteville, Helen Y Figueroa, Wai Haung Yu, Robert A Whittington, Peter Davies, Akihiko Takashima, Ralph A Nixon, Karen E Duff

Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia

麻醉通过低温抑制磷酸酶活性导致 tau 过度磷酸化

Emmanuel Planel, Karl E G Richter, Charles E Nolan, James E Finley, Li Liu, Yi Wen, Pavan Krishnamurthy, Mathieu Herman, Lili Wang, Joel B Schachter, Robert B Nelson, Lit-Fui Lau, Karen E Duff