日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Drug-Like Small Molecules That Inhibit Expression of the Oncogenic MicroRNA-21

抑制致癌性microRNA-21表达的类药小分子

Shortridge, Matthew D; Chaubey, Bhawna; Zhang, Huanyu J; Pavelitz, Thomas; Vidadala, Venkata; Tang, Changyan; Olsen, Gregory L; Calin, George A; Varani, Gabriele

An evolutionarily conserved RNA structure in the functional core of the lincRNA Cyrano

lincRNA Cyrano功能核心中进化保守的RNA结构

Jones, Alisha N; Pisignano, Giuseppina; Pavelitz, Thomas; White, Jessica; Kinisu, Martin; Forino, Nicholas; Albin, Dreycey; Varani, Gabriele

A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing

一种大环肽配体结合致癌性microRNA-21前体并抑制Dicer加工。

Shortridge, Matthew D; Walker, Matthew J; Pavelitz, Tom; Chen, Yu; Yang, Wen; Varani, Gabriele

Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins

利用设计的 RNA 结合蛋白靶向抑制致癌 miR-21 成熟

Yu Chen, Fan Yang, Lorena Zubovic, Tom Pavelitz, Wen Yang, Katherine Godin, Matthew Walker, Suxin Zheng, Paolo Macchi, Gabriele Varani

MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial

在随机CALGB 89803试验中,MRE11缺陷与部分III期结肠癌患者的长期无病生存期和总生存期改善相关。

Pavelitz, Thomas; Renfro, Lindsay; Foster, Nathan R; Caracol, Amber; Welsch, Piri; Lao, Victoria Valinluck; Grady, William B; Niedzwiecki, Donna; Saltz, Leonard B; Bertagnolli, Monica M; Goldberg, Richard M; Rabinovitch, Peter S; Emond, Mary; Monnat, Raymond J Jr; Maizels, Nancy

PGBD5: a neural-specific intron-containing piggyBac transposase domesticated over 500 million years ago and conserved from cephalochordates to humans

PGBD5:一种含有神经特异性内含子的 piggyBac 转座酶,于 5 亿多年前被驯化,并从头索动物到人类一直保留下来

Thomas Pavelitz, Lucas T Gray, Stephanie L Padilla, Arnold D Bailey, Alan M Weiner

The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells

保守的 Cockayne 综合征 B-piggyBac 融合蛋白 (CSB-PGBD3) 影响 DNA 修复并在 CSB 缺陷细胞中诱导干扰素样和先天抗病毒反应

Arnold D Bailey, Lucas T Gray, Thomas Pavelitz, John C Newman, Katsuyoshi Horibata, Kiyoji Tanaka, Alan M Weiner

Tethering of the conserved piggyBac transposase fusion protein CSB-PGBD3 to chromosomal AP-1 proteins regulates expression of nearby genes in humans

保守的 piggyBac 转座酶融合蛋白 CSB-PGBD3 与染色体 AP-1 蛋白的结合可调节人类邻近基因的表达

Lucas T Gray, Kimberly K Fong, Thomas Pavelitz, Alan M Weiner

An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome

在科凯恩综合征中表达的大量进化保守的CSB-PiggyBac融合蛋白

Newman, John C; Bailey, Arnold D; Fan, Hua-Ying; Pavelitz, Thomas; Weiner, Alan M

Human U2 snRNA genes exhibit a persistently open transcriptional state and promoter disassembly at metaphase

人类U2 snRNA基因在有丝分裂中期表现出持续开放的转录状态和启动子解体。

Pavelitz, Thomas; Bailey, Arnold D; Elco, Christopher P; Weiner, Alan M