日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.

磷酸化起始因子 2 α 亚基 (eIF2α) 与鸟嘌呤核苷酸交换因子 eIF2B 的调节亚基紧密结合是抑制翻译起始所必需的

Krishnamoorthy T, Pavitt G D, Zhang F, Dever T E, Hinnebusch A G

Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2

酵母 eIF5 和 eIF2ε 中保守的双元基序(翻译起始过程中的 GTP 酶激活因子和 GDP-GTP 交换因子)介导它们与共同底物 eIF2 的结合。

Asano, K; Krishnamoorthy, T; Phan, L; Pavitt, G D; Hinnebusch, A G

eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange

eIF2 可独立结合两种不同的 eIF2B 亚复合物,这两种亚复合物催化并调节鸟嘌呤核苷酸交换。

Pavitt, G D; Ramaiah, K V; Kimball, S R; Hinnebusch, A G