CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function
CD52 聚糖与 HMGB1 的促炎性 B 盒结合,从而激活 Siglec-10 受体并抑制人 T 细胞功能。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1722056115
Bandala-Sanchez, Esther; G Bediaga, Naiara; Goddard-Borger, Ethan D; Ngui, Katrina; Naselli, Gaetano; Stone, Natalie L; Neale, Alana M; Pearce, Lesley A; Wardak, Ahmad; Czabotar, Peter; Haselhorst, Thomas; Maggioni, Andrea; Hartley-Tassell, Lauren A; Adams, Timothy E; Harrison, Leonard C