日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction

将端到端学习与深度几何势能相结合,用于从头预测RNA结构

Li, Yang; Zhang, Chengxin; Feng, Chenjie; Pearce, Robin; Lydia Freddolino, P; Zhang, Yang

De novo protein fold design through sequence-independent fragment assembly simulations

通过与序列无关的片段组装模拟进行从头蛋白质折叠设计

Pearce, Robin; Huang, Xiaoqiang; Omenn, Gilbert S; Zhang, Yang

Ontogeny of Scaling Factors for Pediatric Physiologically Based Pharmacokinetic Modeling and Simulation: Cytosolic Protein Per Gram of Liver

儿科生理药代动力学建模与模拟中尺度因子的发育:每克肝脏中的胞质蛋白

Stancil, Stephani L; Pearce, Robin E; Staggs, Vincent S; Leeder, J Steven

The Impact of the CYP2D6 "Enhancer" Single Nucleotide Polymorphism on CYP2D6 Activity

CYP2D6“增强子”单核苷酸多态性对CYP2D6活性的影响

Dinh, Jean C; Boone, Erin C; Staggs, Vincent S; Pearce, Robin E; Wang, Wendy Y; Gaedigk, Roger; Leeder, James Steven; Gaedigk, Andrea

Combination Treatment of Withalongolide a Triacetate with Cisplatin Induces Apoptosis by Targeting Translational Initiation, Migration, and Epithelial to Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma

威特隆内酯三乙酸酯与顺铂联合治疗可通过靶向翻译起始、迁移和上皮间质转化诱导头颈部鳞状细胞癌细胞凋亡

Subramanian, Chitra; Spielbauer, Katie K; Pearce, Robin; Kovatch, Kevin J; Prince, Mark E; Timmermann, Barbara N; Cohen, Mark S

Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver

儿科生理药代动力学建模与模拟的尺度因子发展:每克肝脏微粒体蛋白含量

Leeder, J Steven; Dinh, Jean C; Gaedigk, Andrea; Staggs, Vincent S; Prasad, Bhagwat; Pearce, Robin E

Fast and accurate Ab Initio Protein structure prediction using deep learning potentials

利用深度学习势能快速准确地从头预测蛋白质结构

Pearce, Robin; Li, Yang; Omenn, Gilbert S; Zhang, Yang

Utility of the (13) C-pantoprazole breath test as a CYP2C19 phenotyping probe for children

(13)C-泮托拉唑呼气试验作为儿童CYP2C19表型分析探针的实用性

Feldman, Keith; Kearns, Gregory L; Pearce, Robin E; Abdel-Rahman, Susan M; Steven Leeder, James; Friesen, Alec; Staggs, Vincent S; Gaedigk, Andrea; Weigel, Jaylene; Shakhnovich, Valentina

Identification of 13 Guanidinobenzoyl- or Aminidinobenzoyl-Containing Drugs to Potentially Inhibit TMPRSS2 for COVID-19 Treatment

鉴定出13种含胍基苯甲酰基或氨基苯甲酰基的药物,这些药物可能抑制TMPRSS2用于COVID-19治疗。

Huang, Xiaoqiang; Pearce, Robin; Omenn, Gilbert S; Zhang, Yang

Folding non-homologous proteins by coupling deep-learning contact maps with I-TASSER assembly simulations.

通过将深度学习接触图与 I-TASSER 组装模拟相结合来折叠非同源蛋白质

Zheng Wei, Zhang Chengxin, Li Yang, Pearce Robin, Bell Eric W, Zhang Yang