The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation
微生物色氨酸代谢产物吲哚作用于胃肠道,通过增强GLP-1分泌和L细胞分化,改善糖尿病小鼠模型的葡萄糖稳态。
期刊:Diabetologia
影响因子:10.2
doi:10.1007/s00125-026-06688-4
Phuah, Phyllis; Norton, Mariana; Cheng, Sijing; Roberts, Anna G; Pirri, Daniela; Meyer, Leah; Chung, Pei-En; Dunsterville, Cecilia; Karwowski, Rafal; Lam, Brian Y H; Otsubo, Emile; Aleksashina, Sofia; Gribble, Fiona M; Reimann, Frank; Hanyaloglu, Aylin C; Yeo, Giles S H; Bewick, Gavin A; Jones, Ben; Owen, Bryn; Murphy, Kevin G