Colonic spatial single-cell proteomics and murine models link mitochondrial dysfunction to dimeric IgA-secreting plasma cell deficiency in Crohn's disease.
结肠空间单细胞蛋白质组学和鼠模型将线粒体功能障碍与克罗恩病中分泌二聚体 IgA 的浆细胞缺乏联系起来。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69069-w
Raschdorf Annika, de Almeida Larissa Nogueira, Solbach Philipp, Kirstein Martha M, Marquardt Jens U, Schmelter Franziska, Günther Ulrich L, Schlichting Heidi, Hicken Maren, Christiansen Lea, Wiestler Miriam, Tews Hauke C, Bettenworth Dominik, Peipp Matthias, Valerius Thomas, Ragab Mohab, Sauer Thorben, Gemoll Timo, Ehlers Marc, Rosenstiel Philip, Manz Rudolf A, Künstner Axel, Busch Hauke, Sina Christian, Derer Stefanie
