Primary resistance to ICI-based regimens is associated with early longitudinal changes in the fecal microbiome and loss of microbial stability
对免疫检查点抑制剂(ICI)方案的原发性耐药与粪便微生物组的早期纵向变化和微生物稳定性丧失有关。
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doi:10.1101/2025.10.01.25336378
Zhao, Yujie; Naidoo, Jarushka; Conroy, Michael; Ferri, Jacqueline T; Gills, Joell J; Chen, Krista Y; White, James R; Glass, Sara; Assan, William O; Peloza, Kimberly; Schollenberger, Megan D; Sharfman, William H; Marrone, Kristen A; Forde, Patrick; Brahmer, Julie; Anagnostou, Valsalmo; Pardoll, Drew M; Murray, Joseph; Lipson, Evan J; Sears, Cynthia L; Shaikh, Fyza Y