IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells
IFN-α和CD46刺激与活动性狼疮相关,并能诱导天然T调节细胞向1型调节性T细胞(Tr1细胞)分化。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1113301108
Le Buanec, Hélène; Gougeon, Marie-Lise; Mathian, Alexis; Lebon, Pierre; Dupont, Jean-Michel; Peltre, Gabriel; Hemon, Patrice; Schmid, Michel; Bizzini, Bernard; Künding, Thomas; Burny, Arsène; Bensussan, Armand; Amoura, Zahir; Gallo, Robert C; Zagury, Daniel
T细胞
IFN-α
CD46
T细胞
细胞生物学
CD4
免疫/内分泌