日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nuclear and Cytoplasmatic Quantification of Unconjugated, Label-Free Locked Nucleic Acid Oligonucleotides

未偶联、无标记锁核酸寡核苷酸的核质定量分析

Pendergraff, Hannah; Schmidt, Steffen; Vikeså, Jonas; Weile, Christian; Øverup, Charlotte; W Lindholm, Marie; Koch, Troels

Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA

锁核酸间隙聚体及其缀合物能有效沉默ADAM33,一种具有核定位mRNA的哮喘相关金属蛋白酶。

Pendergraff, Hannah M; Krishnamurthy, Pranathi Meda; Debacker, Alexandre J; Moazami, Michael P; Sharma, Vivek K; Niitsoo, Liisa; Yu, Yong; Tan, Yen Nee; Haitchi, Hans Michael; Watts, Jonathan K

Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs.

探索序列长度和组成对单链沉默RNA选择性抑制人类亨廷顿蛋白表达的影响

Hu Jiaxin, Liu Jing, Yu Dongbo, Aiba Yuichiro, Lee Suheung, Pendergraff Hannah, Boubaker Jihane, Artates Jonathan W, Lagier-Tourenne Clotilde, Lima Walt F, Swayze Eric E, Prakash Thazha P, Corey David R

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy

ss-siRNA 等位基因选择性抑制 Ataxin-3 表达:替代基因沉默策略的多种机制

Jing Liu, Dongbo Yu, Yuichiro Aiba, Hannah Pendergraff, Eric E Swayze, Walt F Lima, Jiaxin Hu, Thazha P Prakash, David R Corey

Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression

单链 RNA 利用 RNAi 强效且等位基因选择性地抑制突变型亨廷顿蛋白的表达

Dongbo Yu, Hannah Pendergraff, Jing Liu, Holly B Kordasiewicz, Don W Cleveland, Eric E Swayze, Walt F Lima, Stanley T Crooke, Thazha P Prakash, David R Corey

Antisense and antigene inhibition of gene expression by cell-permeable oligonucleotide-oligospermine conjugates

利用细胞渗透性寡核苷酸-寡精胺缀合物对基因表达进行反义和反义抑制

Gagnon, Keith T; Watts, Jonathan K; Pendergraff, Hannah M; Montaillier, Christophe; Thai, Danielle; Potier, Pierre; Corey, David R

Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat

利用针对扩增的 CAG 重复序列的反义寡核苷酸对突变型亨廷顿蛋白的等位基因选择性抑制

Keith T Gagnon, Hannah M Pendergraff, Glen F Deleavey, Eric E Swayze, Pierre Potier, John Randolph, Eric B Roesch, Jyoti Chattopadhyaya, Masad J Damha, C Frank Bennett, Christophe Montaillier, Marc Lemaitre, David R Corey