Peng Dunfa相关文献与解析，生知库 | 链接生命科学的每一步

Lu, Heng; Ballout, Farah; Chen, Lei; Peng, Dunfa; Chen, Zheng; Soutto, Mohammed; Cao, Longlong; Thangaretnam, Krishnapriya; Gokulan, Ravindran Caspa; Wang, Timothy C; Que, Jianwen; Giordano, Silvia; Washington, Mary Kay; Chen, Xi Steven; Sun, Xiaodian; Ban, Yuguang; McDonald, Oliver Gene; Zaika, Alexander; El-Rifai, Wael

肿瘤

SOX

肿瘤免疫

SOX9

发表日期：2026

文献求助收藏

WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma

WEE1稳定MYC，从而促进食管腺癌的治疗耐药性

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2026.218418

Thangaretnam, Krishnapriya; Islam, Md Obaidul; Lv, Jialun; Zhang, Zhenzhen; Chen, Lei; Ballout, Farah; Lu, Heng; Peng, Dunfa; Zaika, Alexander; El-Rifai, Wael; Giordano, Silvia; Ban, Yuguang; Bilbao, Daniel; Chen, Zheng

CDK1 drives SOX9-mediated chemotherapeutic resistance in gastric cancer.

CDK1 驱动 SOX9 介导的胃癌化疗耐药性。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-025-03523-3

Al-Mathkour Marwah, Chen Zheng, Poveda Julio, Cao Longlong, McDonald Oliver G, Peng Dunfa, Soutto Mohammed, Chen Zhibin, Lu Heng, Guo Yan, Kumar Shria, Zaika Alexander, Giordano Silvia, Zhu Shoumin, El-Rifai Wael

Targeting NEK Kinases in Gastrointestinal Cancers: Insights into Gene Expression, Function, and Inhibitors

靶向NEK激酶治疗胃肠道癌症：基因表达、功能和抑制剂的深入研究

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26051992

Chen, Lei; Lu, Heng; Ballout, Farah; El-Rifai, Wael; Chen, Zheng; Gokulan, Ravindran Caspa; McDonald, Oliver Gene; Peng, Dunfa

Phospho-CREB Regulation on NMDA Glutamate Receptor 2B and Mitochondrial Calcium Uniporter in the Ventrolateral Periaqueductal Gray Controls Chronic Morphine Withdrawal in Male Rats.

磷酸化 CREB 对 NMDA 谷氨酸受体 2B 和线粒体钙单向转运蛋白在腹外侧导水管周围灰质中的调节控制雄性大鼠的慢性吗啡戒断

期刊:Journal of Neuroscience

影响因子:4

doi:10.1523/JNEUROSCI.1934-24.2025

Yi Hyun, Gu Jun, Hamilton Peter J, Liu Shue, Zhu Shoumin, Ikegami Daigo, Hayashi Kentaro, Kashiwagi Yuta, Iida Takafumi, Liu Qiaofeng, Zhu Xun, Tong Xiaoying, Peng Dunfa, Zhuang Gerald Z, Pardo Marta, El-Rifai Wael, Levitt Roy C, Nestler Eric J, Hao Shuanglin

SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation

SOX9 受 AURKA 调控，响应幽门螺杆菌感染，其调控机制是通过 EIF4E 介导的帽依赖性翻译。

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2024.216939

Gomaa, Ahmed; Maacha, Selma; Peng, Dunfa; Soutto, Mohammed; Genoula, Melanie; Bhat, Nadeem; Cao, Longlong; Zhu, Shoumin; Castells, Antoni; Chen, Zhibin; Zaika, Alexander; McDonald, Oliver G; El-Rifai, Wael

Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma

反流条件通过APE1氧化还原功能诱导食管腺癌中E-钙黏蛋白裂解和上皮间质转化（EMT）。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2023-329455

Lu, Heng; Cao, Long Long; Ballout, Farah; Belkhiri, Abbes; Peng, DunFa; Chen, Lei; Chen, Zheng; Soutto, Mohammed; Wang, Timothy C; Que, Jianwen; Giordano, Silvia; Washington, Mary Kay; Chen, Steven; McDonald, Oliver Gene; Zaika, Alexander; El-Rifai, Wael

Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma

在食管腺癌中，DLL1介导的NOTCH信号通路激活是由APE1氧化还原依赖性NF-κB激活所致。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2022-327076

Chen, Lei; Lu, Heng; Peng, Dunfa; Cao, Long Long; Ballout, Farah; Srirmajayam, Kannappan; Chen, Zheng; Bhat, Ajaz; Wang, Timothy C; Capobianco, Anthony; Que, Jianwen; McDonald, Oliver Gene; Zaika, Alexander; Zhang, Shutian; El-Rifai, Wael

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis

幽门螺杆菌诱导的RASAL2通过激活核因子-κB，经由β-catenin信号通路促进胃肿瘤发生

期刊:Gastroenterology

影响因子:25.1

doi:10.1053/j.gastro.2022.01.046

Cao, Longlong; Zhu, Shoumin; Lu, Heng; Soutto, Mohammed; Bhat, Nadeem; Chen, Zheng; Peng, Dunfa; Lin, Jianxian; Lu, Jun; Li, Ping; Zheng, Chaohui; Huang, Changming; El-Rifai, Wael

Unfolded Protein Response Is Activated by Aurora Kinase A in Esophageal Adenocarcinoma.

食管腺癌中，Aurora激酶A激活未折叠蛋白反应

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers14061401

Lu Heng, Gomaa Ahmed, Wang-Bishop Lihong, Ballout Farah, Hu Tianling, McDonald Oliver, Washington Mary Kay, Livingstone Alan S, Wang Timothy C, Peng Dunfa, El-Rifai Wael, Chen Zheng

肿瘤

发表日期：2022

文献求助收藏

Targeting APE1-Redox Function Reverses SOX9-mediated Chemoresistance in Esophageal Adenocarcinoma

靶向 APE1 氧化还原功能可逆转 SOX9 介导的食管腺癌化疗耐药性

WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma

WEE1稳定MYC，从而促进食管腺癌的治疗耐药性

CDK1 drives SOX9-mediated chemotherapeutic resistance in gastric cancer.

CDK1 驱动 SOX9 介导的胃癌化疗耐药性。

Targeting NEK Kinases in Gastrointestinal Cancers: Insights into Gene Expression, Function, and Inhibitors

靶向NEK激酶治疗胃肠道癌症：基因表达、功能和抑制剂的深入研究

Phospho-CREB Regulation on NMDA Glutamate Receptor 2B and Mitochondrial Calcium Uniporter in the Ventrolateral Periaqueductal Gray Controls Chronic Morphine Withdrawal in Male Rats.

磷酸化 CREB 对 NMDA 谷氨酸受体 2B 和线粒体钙单向转运蛋白在腹外侧导水管周围灰质中的调节控制雄性大鼠的慢性吗啡戒断

SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation

SOX9 受 AURKA 调控，响应幽门螺杆菌感染，其调控机制是通过 EIF4E 介导的帽依赖性翻译。

Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma

反流条件通过APE1氧化还原功能诱导食管腺癌中E-钙黏蛋白裂解和上皮间质转化（EMT）。

Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma

在食管腺癌中，DLL1介导的NOTCH信号通路激活是由APE1氧化还原依赖性NF-κB激活所致。

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis

幽门螺杆菌诱导的RASAL2通过激活核因子-κB，经由β-catenin信号通路促进胃肿瘤发生

Unfolded Protein Response Is Activated by Aurora Kinase A in Esophageal Adenocarcinoma.

食管腺癌中，Aurora激酶A激活未折叠蛋白反应