Peng Hwei-Ming相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site

人细胞色素P450 17A1与前列腺癌药物阿比特龙代谢产物的结构揭示了底物结合的可塑性以及第二个结合位点。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2023.102999

Petrunak, Elyse M; Bart, Aaron G; Peng, Hwei-Ming; Auchus, Richard J; Scott, Emily E

细胞生物学

发表日期：2023

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Selectivity of osilodrostat as an inhibitor of human steroidogenic cytochromes P450

奥西洛司他作为人类类固醇生成细胞色素P450抑制剂的选择性

期刊:Journal of Steroid Biochemistry and Molecular Biology

影响因子:2.5

doi:10.1016/j.jsbmb.2023.106316

Valentín-Goyco, Juan; Liu, Jiayan; Peng, Hwei-Ming; Oommen, Jerry; Auchus, Richard J

细胞生物学

发表日期：2023

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Bacterial expression, purification, and reconstitution of human steroid 5α-reductases in phospholipid liposomes and nanodiscs

细菌表达、纯化和重组人类固醇5α-还原酶于磷脂脂质体和纳米盘中

期刊:Methods in Enzymology

doi:10.1016/bs.mie.2023.05.005

Im, Sang-Choul; Valentín-Goyco, Juan; Peng, Hwei-Ming; Auchus, Richard J

发表日期：2023

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Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases

人类固醇5α-还原酶在大肠杆菌中的表达、纯化和功能重建

期刊:Endocrinology

影响因子:3.3

doi:10.1210/endocr/bqaa117

Peng, Hwei-Ming; Valentín-Goyco, Juan; Im, Sang-Choul; Han, Bing; Liu, Jiayan; Qiao, Jie; Auchus, Richard J

发表日期：2020

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Adrenocorticotropin Acutely Regulates Pregnenolone Sulfate Production by the Human Adrenal In Vivo and In Vitro

促肾上腺皮质激素在体内和体外均能急性调节人肾上腺孕烯醇酮硫酸盐的生成

期刊:Journal of Clinical Endocrinology & Metabolism

影响因子:5.1

doi:10.1210/jc.2017-01525

Rege, Juilee; Nanba, Aya T; Auchus, Richard J; Ren, Jianwei; Peng, Hwei-Ming; Rainey, William E; Turcu, Adina F

免疫/内分泌

发表日期：2018

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Catalytic modulation of human cytochromes P450 17A1 and P450 11B2 by phospholipid.

磷脂对人细胞色素 P450 17A1 和 P450 11B2 的催化调节

期刊:Journal of Steroid Biochemistry and Molecular Biology

影响因子:2.5

doi:10.1016/j.jsbmb.2018.03.003

Peng Hwei-Ming, Barlow Chase, Auchus Richard J

细胞生物学

发表日期：2018

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Making water-soluble integral membrane proteins in vivo using an amphipathic protein fusion strategy

利用两亲性蛋白融合策略在体内构建水溶性整合膜蛋白

期刊:Nature Communications

影响因子:15.7

doi:10.1038/ncomms7826

Mizrachi, Dario; Chen, Yujie; Liu, Jiayan; Peng, Hwei-Ming; Ke, Ailong; Pollack, Lois; Turner, Raymond J; Auchus, Richard J; DeLisa, Matthew P

发表日期：2015

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Two surfaces of cytochrome b5 with major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries

细胞色素b5的两个表面分别对CYP3A4催化的类固醇和硝苯地平氧化反应有主要和次要的贡献

期刊:Archives of Biochemistry and Biophysics

doi:10.1016/j.abb.2013.11.001

Peng, Hwei-Ming; Auchus, Richard J

细胞生物学

发表日期：2014

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A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone

A环修饰的甾体唑类化合物保留了与阿比特龙相似的强效且缓慢可逆的CYP17A1抑制作用。

期刊:Journal of Steroid Biochemistry and Molecular Biology

影响因子:2.5

doi:10.1016/j.jsbmb.2014.01.013

Garrido, Mariana; Peng, Hwei-Ming; Yoshimoto, Francis K; Upadhyay, Sunil K; Bratoeff, Eugene; Auchus, Richard J

发表日期：2014

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Modulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitination

神经元型一氧化氮合酶 (nNOS) 血红素/底物结合槽的调控调节 Hsp90 和 Hsp70 蛋白的结合以及 nNOS 的泛素化。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M111.323295

Peng, Hwei-Ming; Morishima, Yoshihiro; Pratt, William B; Osawa, Yoichi

发表日期：2012

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