Penrose Harrison M相关文献与解析，生知库

Correction: Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

更正：结肠癌细胞和癌干细胞中ATGL水平升高会促进代谢和肿瘤发生重编程，而肥胖会加剧这一过程。

Iftikhar, Rida; Penrose, Harrison M; King, Angelle N; Samudre, Joshua S; Collins, Morgan E; Hartono, Alifiani B; Lee, Sean B; Lau, Frank; Baddoo, Melody; Flemington, Erik F; Crawford, Susan E; Savkovic, Suzana D

ATGL

FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis

高脂饮食会降低巨噬细胞中FOXO3的表达，而FOXO3调控结肠炎症和肿瘤发生

期刊:Metabolites

影响因子:3.7

doi:10.3390/metabo12030250

Iftikhar, Rida; Penrose, Harrison M; King, Angelle N; Kim, Yunah; Ruiz, Emmanuelle; Kandil, Emad; Machado, Heather L; Savkovic, Suzana D

Immunology/Inflammation

Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity.

结肠癌细胞和癌症干细胞中 ATGL 水平升高会促进代谢和肿瘤发生重编程，而肥胖会加剧这种重编程

期刊:Oncogenesis

影响因子:6.4

doi:10.1038/s41389-021-00373-4

Iftikhar Rida, Penrose Harrison M, King Angelle N, Samudre Joshua S, Collins Morgan E, Hartono Alifiani B, Lee Sean B, Lau Frank, Baddoo Melody, Flemington Erik F, Crawford Susan E, Savkovic Suzana D

Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

溃疡性结肠炎免疫细胞图谱和差异表达基因特征决定了新的调控因子并预测了生物疗法的临床疗效

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-021-88489-w

Penrose, Harrison M; Iftikhar, Rida; Collins, Morgan E; Toraih, Eman; Ruiz, Emmanuelle; Ungerleider, Nathan; Nakhoul, Hani; Flemington, Erik F; Kandil, Emad; Shah, Shamita B; Savkovic, Suzana D

Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease

细菌 TLR4 和 NOD2 信号通路与活动性炎症性肠病中线粒体能量功能降低有关

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2019.1611152

Ruiz, Emmanuelle; Penrose, Harrison M; Heller, Sandra; Nakhoul, Hani; Baddoo, Melody; Flemington, Erik F; Kandil, Emad; Savkovic, Suzana D

STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells

在原代培养的系膜细胞中，STAT1以双向方式调节干扰素-γ诱导的血管紧张素原和MCP-1的表达。

期刊:Journal of the Renin-Angiotensin-Aldosterone System

影响因子:4.1

doi:10.1177/1470320320946527

Penrose, Harrison M; Katsurada, Akemi; Miyata, Kayoko; Urushihara, Maki; Satou, Ryousuke

High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors.

高脂饮食诱导瘦素和 Wnt 表达：小鼠结肠组织和肿瘤的 RNA 测序和通路分析

期刊:Carcinogenesis

影响因子:2.9

doi:10.1093/carcin/bgx001

Penrose Harrison M, Heller Sandra, Cable Chloe, Nakhoul Hani, Baddoo Melody, Flemington Erik, Crawford Susan E, Savkovic Suzana D

New approach methodologies in Crohn's disease link molecular disease subtypes to clinical outcomes

克罗恩病的新方法将分子疾病亚型与临床结果联系起来

F.O.R.W.A.R.D: A Data-Driven Framework for Network-Based Target Prioritization in Drug Discovery

FORWARD：一种基于网络的药物发现靶点优先级排序的数据驱动框架

FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis.

中性粒细胞中 FOXO3 缺乏会引发结肠炎症和肿瘤发生

Correction: Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

更正：结肠癌细胞和癌干细胞中ATGL水平升高会促进代谢和肿瘤发生重编程，而肥胖会加剧这一过程。

FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis

高脂饮食会降低巨噬细胞中FOXO3的表达，而FOXO3调控结肠炎症和肿瘤发生

Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity.

结肠癌细胞和癌症干细胞中 ATGL 水平升高会促进代谢和肿瘤发生重编程，而肥胖会加剧这种重编程

Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

溃疡性结肠炎免疫细胞图谱和差异表达基因特征决定了新的调控因子并预测了生物疗法的临床疗效

Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease

细菌 TLR4 和 NOD2 信号通路与活动性炎症性肠病中线粒体能量功能降低有关

STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells

在原代培养的系膜细胞中，STAT1以双向方式调节干扰素-γ诱导的血管紧张素原和MCP-1的表达。

High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors.

高脂饮食诱导瘦素和 Wnt 表达：小鼠结肠组织和肿瘤的 RNA 测序和通路分析