日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

TLR7/8 激动剂可增强抗芬太尼疫苗在啮齿动物和猪模型中的功效

Bethany Crouse, Shannon M Miller, Peter Muelken, Linda Hicks, Jennifer R Vigliaturo, Cheryl L Marker, Alonso G P Guedes, Paul R Pentel, Jay T Evans, Mark G LeSage, Marco Pravetoni

Recruiting Sexual and Gender Minority Veterans for Health Disparities Research: Recruitment Protocol of a Web-Based Prospective Cohort Study

招募性少数和性别少数退伍军人参与健康差异研究:基于网络的队列研究招募方案

Fan, Carolyn A; Upham, Michelle; Beaver, Kristine; Dashtestani, Krista; Skiby, Malachi M; Pentel, Kimberly Z; Rhew, Isaac C; Kauth, Michael R; Shipherd, Jillian C; Kaysen, Debra; Simpson, Tracy; Lehavot, Keren

Pre-clinical safety and toxicology profile of a candidate vaccine to treat oxycodone use disorder

治疗羟可酮使用障碍的候选疫苗的临床前安全性和毒理学概况

Fatima A Hamid, Cheryl L Marker, Michael D Raleigh, Aaron Khaimraj, Scott Winston, Paul R Pentel, Marco Pravetoni

Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder

疫苗产生的抗体治疗羟考酮使用障碍的药理机制

Raleigh, M D; King, S J; Baruffaldi, F; Saykao, A; Hamid, F A; Winston, S; LeSage, M G; Pentel, P R; Pravetoni, M

Attenuating nicotine's effects with high affinity human anti-nicotine monoclonal antibodies

利用高亲和力人类抗尼古丁单克隆抗体减弱尼古丁的影响

Michael D Raleigh, Nicola Beltraminelli, Stephanie Fallot, Mark G LeSage, Amy Saykao, Paul R Pentel, Steve Fuller, Thomas Thisted, Zuzanna Biesova, Stephen Horrigan, Darryl Sampey, Bin Zhou, Matthew W Kalnik

Effect of Adjuvant Release Rate on the Immunogenicity of Nanoparticle-Based Vaccines: A Case Study with a Nanoparticle-Based Nicotine Vaccine

佐剂释放速率对纳米颗粒疫苗免疫原性的影响:以纳米颗粒尼古丁疫苗为例

Zhao, Zongmin; Hu, Yun; Harmon, Theresa; Pentel, Paul; Ehrich, Marion; Zhang, Chenming

Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

适合药品生产和临床评估的减少阿片类药物使用障碍的结合疫苗的配方和特性

F Baruffaldi, M D Raleigh, S J King, M J Roslawski, A K Birnbaum, C Hassler, F I Carroll, S P Runyon, S Winston, P R Pentel, M Pravetoni

Rational incorporation of molecular adjuvants into a hybrid nanoparticle-based nicotine vaccine for immunotherapy against nicotine addiction

将分子佐剂合理地整合到基于纳米颗粒的混合尼古丁疫苗中,用于对抗尼古丁成瘾的免疫疗法

Zhao, Zongmin; Harris, Brian; Hu, Yun; Harmon, Theresa; Pentel, Paul R; Ehrich, Marion; Zhang, Chenming

The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

尼古丁降解酶NicA2可降低大鼠血液中的尼古丁水平、减少尼古丁向大脑的分布,并减弱大鼠对尼古丁的辨别和强化作用。

Pentel, Paul R; Raleigh, Michael D; LeSage, Mark G; Thisted, Thomas; Horrigan, Stephen; Biesova, Zuzana; Kalnik, Matthew W

Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse

羟可酮疫苗的安全性和有效性:解决阿片类药物滥用带来的一些独特问题

M D Raleigh, S J Peterson, M Laudenbach, F Baruffaldi, F I Carroll, S D Comer, H A Navarro, T L Langston, S P Runyon, S Winston, M Pravetoni, P R Pentel