日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan

噻二唑烷酮 (TDZD) 类似物可抑制多种神经退行性疾病模型中聚集介导的病理过程,并延长秀丽隐杆线虫的寿命和健康寿命。

Kakraba, Samuel; Ayyadevara, Srinivas; Mainali, Nirjal; Balasubramaniam, Meenakshisundaram; Bowroju, Suresh; Penthala, Narsimha Reddy; Atluri, Ramani; Barger, Steven W; Griffin, Sue T; Crooks, Peter A; Shmookler Reis, Robert J

The Impact of Coronavirus Disease 2019 on US Emergency Departments

2019冠状病毒病对美国急诊科的影响

Alvarez Romero, Manuel G; Penthala, Chandra; Zeller, Scott L; Wilson, Michael P

Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion

利用生物样本库中胶质母细胞瘤患者来源的类器官作为精准医学模型研究侵袭抑制

Darrigues, Emilie; Zhao, Edward H; De Loose, Annick; Lee, Madison P; Borrelli, Michael J; Eoff, Robert L; Galileo, Deni S; Penthala, Narsimha R; Crooks, Peter A; Rodriguez, Analiz

Aging-associated skeletal muscle defects in HER2/Neu transgenic mammary tumor model

HER2/Neu 转基因乳腺肿瘤模型中与衰老相关的骨骼肌缺陷

Ruizhong Wang, Brijesh Kumar, Poornima Bhat-Nakshatri, Mayuri S Prasad, Max H Jacobsen, Gabriela Ovalle, Calli Maguire, George Sandusky, Trupti Trivedi, Khalid S Mohammad, Theresa Guise, Narsimha R Penthala, Peter A Crooks, Jianguo Liu, Teresa Zimmers, Harikrishna Nakshatri

Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone

评估BT2-peg2(一种潜在的靶向递送抗生素至骨骼的载体)的骨骼和肾脏毒性

Albayati, Zaineb A F; Penthala, Narsimha R; Bommagani, Shobanbabu; Post, Ginell R; Smeltzer, Mark S; Crooks, Peter A

Oxone(®)-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II

Oxone®介导的TEMPO氧化纤维素纳米材料I型和II型

Moore Ii, John P; Dachavaram, Soma Shekar; Bommagani, Shobanbabu; Penthala, Narsimha Reddy; Venkatraman, Priya; Foster, E Johan; Crooks, Peter A; A Hestekin, Jamie

Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation

设计并合成新型杂合8-羟基喹啉-吲哚衍生物作为Aβ自聚集和金属螯合诱导Aβ聚集的抑制剂

Bowroju, Suresh K; Mainali, Nirjal; Ayyadevara, Srinivas; Penthala, Narsimha R; Krishnamachari, Sesha; Kakraba, Samuel; Shmookler Reis, Robert J; Crooks, Peter A

Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs

GSK3β的结构模型表明,TDZD类似物结合的靶点是其非活性(DFG-out)构象。

Balasubramaniam, Meenakshisundaram; Mainali, Nirjal; Bowroju, Suresh Kuarm; Atluri, Paavan; Penthala, Narsimha Reddy; Ayyadevera, Srinivas; Crooks, Peter A; Shmookler Reis, Robert J

7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands

7-氮杂吲哚喹啉酮(7-AIQD):一类新型大麻素1(CB1)和大麻素2(CB2)受体配体

Penthala, Narsimha Reddy; Shoeib, Amal; Dachavaram, Soma Shekar; Cabanlong, Christian V; Yang, Jingfang; Zhan, Chang-Guo; Prather, Paul L; Crooks, Peter A

Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms

吲哚衍生物对人类DNA聚合酶Eta和Kappa的抑制作用是通过不同的机制实现的。

Ketkar, Amit; Maddukuri, Leena; Penthala, Narsimha R; Reed, Megan R; Zafar, Maroof K; Crooks, Peter A; Eoff, Robert L