日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells

利用短读长RNA测序技术在神经分化的人类诱导多能干细胞中确定剪接转换反义寡核苷酸的脱靶效应

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddaf153
Kuijper, Elsa C; van der Graaf, Linda; Pepers, Barry A; Guimarães Ramos, Mariana; Korhorn, Sylvia; Toonen, Lodewijk J A; Cats, Davy; Buijsen, Ronald A M; Mina, Eleni; Mei, Hailiang; van Roon-Mom, Willeke M C
细胞生物学
发育与干细胞
Sequencing
干细胞
发表日期：2025
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Calcium-Enhanced Medium-Based Delivery of Splice Modulating Antisense Oligonucleotides in 2D and 3D hiPSC-Derived Neuronal Models

在二维和三维hiPSC衍生神经元模型中，利用钙增强培养基递送剪接调节反义寡核苷酸

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines12091933
Ronald A M Buijsen ，Linda M van der Graaf ，Elsa C Kuijper ，Barry A Pepers ，Elena Daoutsali ，Lotte Weel ，Vered Raz ，David A Parfitt ，Willeke M C van Roon-Mom
神经科学
发表日期：2024
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Amyloid beta accumulations and enhanced neuronal differentiation in cerebral organoids of Dutch-type cerebral amyloid angiopathy patients

荷兰型脑淀粉样血管病患者脑类器官中淀粉样β蛋白的积累和神经元分化增强

期刊:Frontiers in Aging Neuroscience
影响因子:4.1
doi:10.3389/fnagi.2022.1048584
Elena Daoutsali, Barry A Pepers, Stavros Stamatakis, Linda M van der Graaf, Gisela M Terwindt, David A Parfitt, Ronald A M Buijsen, Willeke M C van Roon-Mom
神经
发表日期：2023
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Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy

反义寡核苷酸诱导的淀粉样前体蛋白剪接调节作为荷兰型脑淀粉样血管病的治疗方法

期刊:Nucleic Acid Therapeutics
影响因子:4
doi:10.1089/nat.2021.0005
Elena Daoutsali, Tsinatkeab T Hailu, Ronald A M Buijsen, Barry A Pepers, Linda M van der Graaf, Marcel M Verbeek, Daniel Curtis, Thomas de Vlaam, Willeke M C van Roon-Mom
信号转导
发表日期：2021
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Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA-minus RNA sequencing data

多聚腺苷酸化RNA和核糖体RNA-RNA测序数据中的融合转录本及其基因组断点

期刊:Gigascience
影响因子:3.9
doi:10.1093/gigascience/giab080
Hoogstrate, Youri; Komor, Malgorzata A; Böttcher, René; van Riet, Job; van de Werken, Harmen J G; van Lieshout, Stef; Hoffmann, Ralf; van den Broek, Evert; Bolijn, Anne S; Dits, Natasja; Sie, Daoud; van der Meer, David; Pepers, Floor; Bangma, Chris H; van Leenders, Geert J L H; Smid, Marcel; French, Pim J; Martens, John W M; van Workum, Wilbert; van der Spek, Peter J; Janssen, Bart; Caldenhoven, Eric; Rausch, Christian; de Jong, Mark; Stubbs, Andrew P; Meijer, Gerrit A; Fijneman, Remond J A; Jenster, Guido W
发表日期：2021
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Generation of 3 human induced pluripotent stem cell lines LUMCi005-A, B and C from a Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch type patient

从遗传性脑出血伴淀粉样变性荷兰型患者中生成 3 种人类诱导性多能干细胞系 LUMCi005-A、B 和 C

期刊:Stem Cell Research
影响因子:0.8
doi:10.1016/j.scr.2018.101359
Elena Daoutsali, Ronald A M Buijsen, Simone van de Pas, Anke 't Jong, Harald Mikkers, Tom Brands, Bert Eussen, Annelies de Klein, Linda M van der Graaf, Barry A Pepers, Christian Freund, Gisela M Terwindt, Valeria V Orlova, Willeke M C van Roon-Mom
发育与干细胞
干细胞
Human
发表日期：2019
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Generation of 5 induced pluripotent stem cell lines, LUMCi007-A and B and LUMCi008-A, B and C, from 2 patients with Huntington disease

从 2 名亨廷顿病患者体内生成 5 种诱导性多能干细胞系，LUMCi007-A 和 B 以及 LUMCi008-A、B 和 C

期刊:Stem Cell Research
影响因子:0.8
doi:10.1016/j.scr.2019.101498
Linda M van der Graaf, Sarah L Gardiner, Merve Tok, Tom Brands, Merel W Boogaard, Barry A Pepers, Bert Eussen, Annelies de Klein, N Ahmad Aziz, Christian Freund, Ronald A M Buijsen, Willeke M C van Roon-Mom
发育与干细胞
干细胞
发表日期：2019
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Generation of 3 spinocerebellar ataxia type 1 (SCA1) patient-derived induced pluripotent stem cell lines LUMCi002-A, B, and C and 2 unaffected sibling control induced pluripotent stem cell lines LUMCi003-A and B

产生 3 种脊髓小脑共济失调 1 型 (SCA1) 患者来源的诱导性多能干细胞系 LUMCi002-A、B 和 C，以及 2 种未受影响的同胞对照诱导性多能干细胞系 LUMCi003-A 和 B

期刊:Stem Cell Research
影响因子:0.8
doi:10.1016/j.scr.2018.03.018
Ronald A M Buijsen, Sarah L Gardiner, Marga J Bouma, Linda M van der Graaf, Merel W Boogaard, Barry A Pepers, Bert Eussen, Annelies de Klein, Christian Freund, Willeke M C van Roon-Mom
发育与干细胞
干细胞
发表日期：2018
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Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates

死后延迟对人类对照和亨廷顿病脑裂解物中 N 端亨廷顿蛋白片段的影响

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0178556
Menno H Schut, Stefano Patassini, Eric H Kim, Jocelyn Bullock, Henry J Waldvogel, Richard L M Faull, Barry A Pepers, Johan T den Dunnen, Gert-Jan B van Ommen, Willeke M C van Roon-Mom
信号转导
Human
发表日期：2017
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Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

症状性骨关节炎中DIO2易感性的潜在分子机制

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2013-204739
Bomer, Nils; den Hollander, Wouter; Ramos, Yolande F M; Bos, Steffan D; van der Breggen, Ruud; Lakenberg, Nico; Pepers, Barry A; van Eeden, Annelies E; Darvishan, Arash; Tobi, Elmar W; Duijnisveld, Bouke J; van den Akker, Erik B; Heijmans, Bastiaan T; van Roon-Mom, Willeke Mc; Verbeek, Fons J; van Osch, Gerjo J V M; Nelissen, Rob G H H; Slagboom, P Eline; Meulenbelt, Ingrid
关节炎
发表日期：2015
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