日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic evidence for serum amyloid P component as a drug target in neurodegenerative disorders

血清淀粉样蛋白P组分作为神经退行性疾病药物靶点的遗传学证据

Schmidt, A Floriaan; Finan, Chris; Chopade, Sandesh; Ellmerich, Stephan; Rossor, Martin N; Hingorani, Aroon D; Pepys, Mark B

Serum amyloid P component accumulates and persists in neurones following traumatic brain injury

创伤性脑损伤后,血清淀粉样蛋白P成分会在神经元中积聚并持续存在。

Yip, Ping K; Liu, Zhou-Hao; Hasan, Shumaila; Pepys, Mark B; Uff, Christopher E G

Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders

血清淀粉样蛋白P组分作为治疗神经退行性疾病药物靶点的遗传学证据

Schmidt, A Floriaan; Finan, Chris; Chopade, Sandesh; Ellmerich, Stephan; Rossor, Martin N; Hingorani, Aroon D; Pepys, Mark B

C-reactive protein predicts outcome in COVID-19: is it also a therapeutic target?

C反应蛋白可预测COVID-19的预后:它也是治疗靶点吗?

Pepys, Mark B

Dementia in the older population is associated with neocortex content of serum amyloid P component.

老年人群的痴呆症与新皮质中血清淀粉样蛋白P成分的含量有关

Ellmerich Stephan, Taylor Graham W, Richardson Connor D, Minett Thais, Schmidt Amand Floriaan, Brayne Carol, Matthews Fiona E, Ince Paul G, Wharton Stephen B, Pepys Mark B

Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1.

随机 I 期试验 HIV-CORE 003:血清淀粉样蛋白 P 成分的消耗和 DNA 疫苗对 HIV-1 的免疫原性

Borthwick Nicola J, Lane Thirusha, Moyo Nathifa, Crook Alison, Shim Jung Min, Baines Ian, Wee Edmund G, Hawkins Philip N, Gillmore Julian D, Hanke Tomáš, Pepys Mark B

Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies

通过对淀粉样组织活检样本进行脱细胞处理来提高蛋白质组学分型的准确性

Mangione, P Patrizia; Mazza, Giuseppe; Gilbertson, Janet A; Rendell, Nigel B; Canetti, Diana; Giorgetti, Sofia; Frenguelli, Luca; Curti, Marco; Rezk, Tamer; Raimondi, Sara; Pepys, Mark B; Hawkins, Philip N; Gillmore, Julian D; Taylor, Graham W; Pinzani, Massimo; Bellotti, Vittorio

Pharmacological removal of serum amyloid P component from intracerebral plaques and cerebrovascular Aβ amyloid deposits in vivo

体内药理学方法清除脑内斑块和脑血管Aβ淀粉样蛋白沉积物中的血清淀粉样蛋白P成分

Al-Shawi, Raya; Tennent, Glenys A; Millar, David J; Richard-Londt, Angela; Brandner, Sebastian; Werring, David J; Simons, J Paul; Pepys, Mark B

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

一种新型的机械酶促切割机制是转甲状腺素蛋白淀粉样变性的基础。

Marcoux, Julien; Mangione, P Patrizia; Porcari, Riccardo; Degiacomi, Matteo T; Verona, Guglielmo; Taylor, Graham W; Giorgetti, Sofia; Raimondi, Sara; Sanglier-Cianférani, Sarah; Benesch, Justin L P; Cecconi, Ciro; Naqvi, Mohsin M; Gillmore, Julian D; Hawkins, Philip N; Stoppini, Monica; Robinson, Carol V; Pepys, Mark B; Bellotti, Vittorio

Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction

多核巨细胞专门用于补体介导的吞噬作用和大型靶标的破坏

Milde, Ronny; Ritter, Julia; Tennent, Glenys A; Loesch, Andrzej; Martinez, Fernando O; Gordon, Siamon; Pepys, Mark B; Verschoor, Admar; Helming, Laura