日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The DREAM complex links somatic mutation, lifespan, and disease

DREAM复合体将体细胞突变、寿命和疾病联系起来

Koch, Zane; Nandi, Shuvro P; Licon, Kate; Bujarrabal-Dueso, Arturo; Meyer, David H; Saeed, Safa; Perampalam, Pirunthan; Dick, Frederick A; Schumacher, Björn; Alexandrov, Ludmil B; Ideker, Trey

Inhibition of GPX4 enhances CDK4/6 inhibitor and endocrine therapy activity in breast cancer

抑制 GPX4 可增强乳腺癌中 CDK4/6 抑制剂和内分泌治疗的活性

M T Herrera-Abreu, J Guan, U Khalid, J Ning, M R Costa, J Chan, Q Li, J-P Fortin, W R Wong, P Perampalam, A Biton, W Sandoval, J Vijay, M Hafner, R Cutts, G Wilson, J Frankum, T I Roumeliotis, J Alexander, O Hickman, R Brough, S Haider, J Choudhary, C J Lord, A Swain, C Metcalfe, N C Turner0

Netrin signaling mediates survival of dormant epithelial ovarian cancer cells

Netrin信号通路介导休眠上皮性卵巢癌细胞的存活。

Pirunthan Perampalam ,James I MacDonald ,Komila Zakirova ,Daniel T Passos ,Sumaiyah Wasif ,Yudith Ramos-Valdes ,Maeva Hervieu ,Patrick Mehlen ,Rob Rottapel ,Benjamin Gibert ,Rohann J M Correa ,Trevor G Shepherd ,Frederick A Dick

GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens

GO-CRISPR:一种高度控制的工作流程,用于在功能丧失筛选中发现基因的必要性

Pirunthan Perampalam, James I McDonald, Frederick A Dick

A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies

用于跨核酸酶和技术设计 CRISPR 引导 RNA 的综合性 Bioconductor 生态系统

Hoberecht, Luke; Perampalam, Pirunthan; Lun, Aaron; Fortin, Jean-Philippe

Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice

破坏 DREAM 转录抑制复合物可诱导小鼠载脂蛋白过度表达和系统性淀粉样变性

Pirunthan Perampalam, Haider M Hassan, Grace E Lilly, Daniel T Passos, Joseph Torchia, Patti K Kiser, Andrea Bozovic, Vathany Kulasingam, Frederick A Dick

BEAVR: a browser-based tool for the exploration and visualization of RNA-seq data

BEAVR:一款基于浏览器的RNA-seq数据探索和可视化工具

Perampalam, Pirunthan; Dick, Frederick A

A case of Klinefelter syndrome with hypersexual desire

一例伴有性欲亢进的克氏综合征病例

Okolie, Kingsley; Perampalam, Sumathy; Barker, Anthony; Nolan, Christopher J

An evolved ribosome-inactivating protein targets and kills human melanoma cells in vitro and in vivo

一种进化的核糖体失活蛋白可以在体内和体外靶向并杀死人类黑色素瘤细胞

Melissa C Cheung, Leigh Revers, Subodini Perampalam, Xin Wei, Reza Kiarash, David E Green, Aws Abdul-Wahid, Jean Gariépy