日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency, and cell death

CRISPRa介导的Dux-MERVL轴在2C样状态、全能性和细胞死亡中的解缠。

Paul Chammas,Sheila Q Xie,Lessly P Sepulveda-Rincon,Bryony J Leeke,Marian H Dore,Dirk Dormann,Ryan T Wagner,Ning Chang,Peter L Jones,Michael T McManus,Mohammad M Karimi,George Young,Michelle Percharde

SMARCA4 regulates the NK-mediated killing of senescent cells

SMARCA4 调控 NK 细胞介导的衰老细胞杀伤作用

Virinder Reen ,Mariantonietta D'Ambrosio ,Pia Pernille Søgaard ,Katie Tyson ,Bryony J Leeke ,Isabelle Clément ,Isabel C A Dye ,Joaquim Pombo ,Adam Kuba ,Yemin Lan ,Joanna Burr ,Ida C Bomann ,Maria Kalyva ,Jodie Birch ,Sanjay Khadayate ,George Young ,Diane Provencher ,Anne-Marie Mes-Masson ,Santiago Vernia ,Nicholas McGranahan ,Hugh J M Brady ,Francis Rodier ,Raffaella Nativio ,Michelle Percharde ,Iain A McNeish ,Jesús Gil

A dual enhancer-attenuator element ensures transient Cdx2 expression during mouse posterior body formation.

双增强子-衰减子元件确保小鼠后体形成过程中 Cdx2 的瞬时表达。

Amblard Irène, Baranasic Damir, Xie Sheila Q, Moyon Benjamin, Percharde Michelle, Lenhard Boris, Metzis Vicki

Emerging roles for the nucleolus in development and stem cells

核仁在发育和干细胞中的新兴作用

Leeke, Bryony J; Staffhorst, Imke; Percharde, Michelle

Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development

多能干细胞中脂滴的动态增大和动员协调小鼠植入前后发育过程中的形态发生

King Hang Tommy Mau, Donja Karimlou, David Barneda, Vincent Brochard, Christophe Royer, Bryony Leeke, Roshni A de Souza, Mélanie Pailles, Michelle Percharde, Shankar Srinivas, Alice Jouneau, Mark Christian, Véronique Azuara

Nucleolar-based Dux repression is essential for embryonic two-cell stage exit

基于核仁的 Dux 抑制对于胚胎退出双细胞阶段至关重要

Sheila Q Xie, Bryony J Leeke, Chad Whilding, Ryan T Wagner, Ferran Garcia-Llagostera, YiXuan Low, Paul Chammas, Nathan T-F Cheung, Dirk Dormann, Michael T McManus, Michelle Percharde

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

L1 和 B1/Alu 重复序列的同型聚集将三维基因组分隔开来

Lu, J Yuyang; Chang, Lei; Li, Tong; Wang, Ting; Yin, Yafei; Zhan, Ge; Han, Xue; Zhang, Ke; Tao, Yibing; Percharde, Michelle; Wang, Liang; Peng, Qi; Yan, Pixi; Zhang, Hui; Bi, Xianju; Shao, Wen; Hong, Yantao; Wu, Zhongyang; Ma, Runze; Wang, Peizhe; Li, Wenzhi; Zhang, Jing; Chang, Zai; Hou, Yingping; Zhu, Bing; Ramalho-Santos, Miguel; Li, Pilong; Xie, Wei; Na, Jie; Sun, Yujie; Shen, Xiaohua

Depletion of nuclear LINE1 RNA in mouse ESCs and embryos

小鼠 ESC 和胚胎中 LINE1 RNA 的消耗

Michelle Percharde, Chih-Jen Lin, Miguel Ramalho-Santos

Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation

基因组重复对具有不同功能的基因进行分类,以便进行协同调控

J Yuyang Lu, Wen Shao, Lei Chang, Yafei Yin, Tong Li, Hui Zhang, Yantao Hong, Michelle Percharde, Lerui Guo, Zhongyang Wu, Lichao Liu, Wei Liu, Pixi Yan, Miguel Ramalho-Santos, Yujie Sun, Xiaohua Shen

Delineating the early transcriptional specification of the mammalian trachea and esophagus

阐明哺乳动物气管和食管的早期转录特化

Akela Kuwahara,Ace E Lewis,Coohleen Coombes,Fang-Shiuan Leung,Michelle Percharde,Jeffrey O Bush