日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread

前馈半胱氨酸调节维持黑色素瘤分化状态并限制转移扩散

Deyang Yu, Jiaxin Liang, Hans R Widlund, Pere Puigserver

Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism

肝线粒体嵴组织蛋白 MIC19 通过改变核苷酸代谢促进能量消耗和行人运动

Jee Hyung Sohn, Beste Mutlu, Pedro Latorre-Muro, Jiaxin Liang, Christopher F Bennett, Kfir Sharabi, Noa Kantorovich, Mark Jedrychowski, Steven P Gygi, Alexander S Banks, Pere Puigserver

Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas

PGC1α(PPARGC1A)的表观遗传抑制导致 BRAF 治疗耐药性黑色素瘤对 HMGCR 抑制剂产生附带敏感性

Jiaxin Liang, Deyang Yu, Chi Luo, Christopher Bennett, Mark Jedrychowski, Steve P Gygi, Hans R Widlund, Pere Puigserver

Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival

四环素激活线粒体质量控制并减少内质网应激以促进细胞存活

Conor T Ronayne, Thomas D Jackson, Christopher F Bennett, Elizabeth A Perry, Noa Kantorovic, Pere Puigserver

Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

四环素依赖性抑制线粒体疾病突变细胞中的线粒体核糖体蛋白延长可抑制IRE1α以促进细胞存活

Conor T Ronayne, Christopher F Bennett, Elizabeth A Perry, Noa Kantorovich, Pere Puigserver

A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation

冷应激诱导的 PERK/OGT 轴控制 TOM70 辅助的线粒体蛋白质导入和嵴形成

Pedro Latorre-Muro, Katherine E O'Malley, Christopher F Bennett, Elizabeth A Perry, Eduardo Balsa, Clint D J Tavares, Mark Jedrychowski, Steven P Gygi, Pere Puigserver

Tetracyclines promote survival and fitness in mitochondrial disease models

四环素类药物可促进线粒体疾病模型中的存活和适应性

Elizabeth A Perry # ,Christopher F Bennett # ,Chi Luo ,Eduardo Balsa ,Mark Jedrychowski ,Katherine E O'Malley ,Pedro Latorre-Muro ,Richard Porter Ladley ,Kamar Reda ,Peter M Wright ,Steven P Gygi ,Andrew G Myers ,Pere Puigserver

Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly

过氧化物酶体衍生的醚磷脂将核苷酸与呼吸体组装连接起来

Christopher F Bennett, Katherine E O'Malley, Elizabeth A Perry, Eduardo Balsa, Pedro Latorre-Muro, Christopher L Riley, Chi Luo, Mark Jedrychowski, Steven P Gygi, Pere Puigserver

Structure-Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production

胰高血糖素诱导葡萄糖生成的抑制剂 SR18292 (16) 的构效关系和生物学研究

Hua Lin, Kfir Sharabi, Li Lin, Claudia Ruiz, Di Zhu, Michael D Cameron, Scott J Novick, Patrick R Griffin, Pere Puigserver, Theodore M Kamenecka

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death

线粒体疾病复合物 I 中 NADPH 生成缺陷会导致炎症和细胞死亡

Eduardo Balsa, Elizabeth A Perry, Christopher F Bennett, Mark Jedrychowski, Steven P Gygi, John G Doench, Pere Puigserver