The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts
氯吡格雷的活性代谢物可破坏P2Y12受体寡聚体,并将其从脂筏中分离出来。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0510446103
Savi, Pierre; Zachayus, Jean-Luc; Delesque-Touchard, Nathalie; Labouret, Catherine; Hervé, Caroline; Uzabiaga, Marie-Françoise; Pereillo, Jean-Marie; Culouscou, Jean-Michel; Bono, Françoise; Ferrara, Pascual; Herbert, Jean-Marc