日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Advances and applications of gut organoids: modeling intestinal diseases and therapeutic development

肠道类器官的研究进展与应用:肠道疾病建模与治疗研发

Xu, Xiaoting; Zhang, Yuping; Huang, Guoxin; Perekatt, Ansu; Wang, Yan; Chen, Lei

Metabolic regulation of intestinal homeostasis: molecular and cellular mechanisms and diseases

肠道稳态的代谢调控:分子和细胞机制及疾病

Zhang, Ruolan; Perekatt, Ansu; Chen, Lei

Epithelial-specific loss of Smad4 alleviates the fibrotic response in an acute colitis mouse model

上皮细胞特异性缺失Smad4可减轻急性结肠炎小鼠模型中的纤维化反应。

Hashemi, Zahra; Hui, Thompson; Wu, Alex; Matouba, Dahlia; Zukowski, Steven; Nejati, Shima; Lim, Crystal; Bruzzese, Julianna; Lin, Cindy; Seabold, Kyle; Mills, Connor; Wrath, Kylee; Wang, Haoyu; Wang, Hongjun; Verzi, Michael P; Perekatt, Ansu

Smad4 Loss in the Mouse Intestinal Epithelium Alleviates the Pathological Fibrotic Response to Injury in the Colon

小鼠肠上皮细胞中Smad4的缺失可减轻结肠损伤后的病理性纤维化反应

Hashemi, Zahra; Hui, Thompson; Wu, Alex; Matouba, Dahlia; Zukowski, Steven; Nejati, Shima; Lim, Crystal; Bruzzese, Julianna; Seabold, Kyle; Mills, Connor; Lin, Cindy; Wrath, Kylee; Wang, Haoyu; Wang, Hongjun; Verzi, Michael P; Perekatt, Ansu

In Vitro Organoid-Based Assays Reveal SMAD4 Tumor-Suppressive Mechanisms for Serrated Colorectal Cancer Invasion

体外类器官实验揭示SMAD4在锯齿状结直肠癌侵袭中的肿瘤抑制机制

Tong, Kevin; Bandari, Manisha; Carrick, Jillian N; Zenkevich, Anastasia; Kothari, Om A; Shamshad, Eman; Stefanik, Katarina; Haro, Katherine S; Perekatt, Ansu O; Verzi, Michael P

TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration

TGFB1诱导胎儿重编程并增强肠道再生

Lei Chen, Abigail Dupre, Xia Qiu, Oscar Pellon-Cardenas, Katherine D Walton, Jianming Wang, Ansu O Perekatt, Wenwei Hu, Jason R Spence, Michael P Verzi

3D Culturing of Organoids from the Intestinal Villi Epithelium Undergoing Dedifferentiation.

肠绒毛上皮去分化过程中类器官的三维培养

Li Christina, Shah Jeel, Wrath Kylee, Matouba Dahlia, Mills Connor, Punnath Kishore, Perekatt Ansu

A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity

一个增强的 HNF4-SMAD4 前馈模块稳定了肠细胞的特性

Lei Chen ,Natalie H Toke ,Shirley Luo ,Roshan P Vasoya ,Robert L Fullem ,Aditya Parthasarathy ,Ansu O Perekatt ,Michael P Verzi

SMAD family member 3 (SMAD3) and SMAD4 repress HIF2α-dependent iron-regulatory genes

SMAD 家族成员 3 (SMAD3) 和 SMAD4 抑制 HIF2α 依赖性铁调节基因

Xiaoya Ma, Nupur K Das, Cristina Castillo, Ayla Gourani, Ansu O Perekatt, Michael P Verzi, Yatrik M Shah

SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium

SMAD4 抑制分化肠道上皮中 WNT 驱动的去分化和致癌作用

Ansu O Perekatt, Pooja P Shah, Shannon Cheung, Nidhi Jariwala, Alex Wu, Vishal Gandhi, Namit Kumar, Qiang Feng, Neeket Patel, Lei Chen, Shilpy Joshi, Anbo Zhou, M Mark Taketo, Jinchuan Xing, Eileen White, Nan Gao, Michael L Gatza, Michael P Verzi